木樨草素与铅（II）的络合作用：光谱学特征和理论研究。
Complexation of luteolin with lead (II): Spectroscopy characterization and theoretical researches.
机构信息
School of Chemical Engineering, Northwest University, 229 North TaiBai Road, Xi'an 710069, China.
College of Chemistry and Chemical Engineering, Yulin University, Yulin 719000, China.
出版信息
J Inorg Biochem. 2019 Apr;193:25-30. doi: 10.1016/j.jinorgbio.2019.01.007. Epub 2019 Jan 15.
The interactions of (CHCOO)Pb·3HO (lead acetate trihydrate) with luteolin, 5,7,3',4'-tetrahydroxyflavone, were investigated in methanol solution. The spectroscopy (UV-Vis, FT-IR, HPLC-MS, H NMR) and elemental analysis were adopted to assess the interaction of luteolin and Pb(II). The results show that luteolin reacts with Pb(II) through the chelating sites of 4‑carbonyl and 5-hydroxy in two luteolin molecules. The structures, energies, CDA (charge decomposition analysis) and orbitals analysis of the ligand and complex have been analyzed according to quantum-chemical calculation, which is further proofed that luteolin molecule can effectively chelate Pb(II) by 5-hydroxyl-4-oxo chelating site. It is speculated that luteolin has a high potential of becoming a health care product to eliminate lead cation in the future.
在甲醇溶液中研究了（CHCOO）Pb·3HO（三水合醋酸铅）与木犀草素（5,7,3',4'-四羟基黄酮）的相互作用。采用光谱（UV-Vis、FT-IR、HPLC-MS、H NMR）和元素分析来评估木犀草素与 Pb(II) 的相互作用。结果表明，木犀草素通过两个木犀草素分子中的 4-羰基和 5-羟基的螯合位点与 Pb(II) 反应。根据量子化学计算，对配体和配合物的结构、能量、CDA（电荷分解分析）和轨道分析进行了分析，进一步证明了木犀草素分子可以通过 5-羟基-4-氧螯合位点有效地螯合 Pb(II)。推测木犀草素有成为未来消除铅阳离子的保健品的高潜力。
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