Zhou Xian, Li Chun-Guang, Chang Dennis, Bensoussan Alan
NICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, Australia.
Medicines (Basel). 2019 Jan 18;6(1):14. doi: 10.3390/medicines6010014.
Traditional Chinese medicine (TCM) is not only used prevalently in Asian countries but has also gained a stable market globally. As a principal form of TCM, Chinese herbal medicine (CHM) is comprised of treatments using multiple Chinese herbs which have complex chemical profiles. Due to a lack of understanding of its modality and a lack of standardization, there are significant challenges associated with regulating CHM's safety for practice and understanding its mechanisms of efficacy. Currently, there are many issues that need to be overcome in regard to the safety and efficacy of CHM for the further development of evidence-based practices. There is a need to better understand the mechanisms behind the efficacy of CHM, and develop proper quality standards and regulations to ensure a similar safety standard as Western drugs. This paper outlines the status of CHM in terms of its safety and efficacy and attempts to provide approaches to address these issues.
传统中医（TCM）不仅在亚洲国家广泛使用，而且在全球也获得了稳定的市场。作为中医的主要形式，中药（CHM）由多种具有复杂化学成分的中药材组成。由于对其作用方式缺乏了解以及缺乏标准化，在规范中药临床应用安全性和理解其疗效机制方面存在重大挑战。目前，在基于循证医学实践的进一步发展中，中药的安全性和有效性方面存在许多需要克服的问题。有必要更好地理解中药疗效背后的机制，并制定适当的质量标准和规范，以确保与西药相似的安全标准。本文概述了中药在安全性和有效性方面的现状，并试图提供解决这些问题的方法。
