Vakhliev V D, Bogatyrev I V, Uchaĭkina L V, Syrkin A L
Kardiologiia. 1988 Oct;28(10):36-9.
Single intravenous doses of isoptin (10 mg) and obsidan (5 mg) were tested for their effects on hemodynamic and coronary blood flow parameters in 35 patients with coronary heart disease and functional classes II-III angina pectoris of effort. In most cases, hemodynamic and coronary blood flow responses to the drug administered were found to be identical. It was concluded that isoptin was effective as an antianginal agent in eukinetic hemodynamics, obsidan, in hyperkinetic one.
对35例患有冠心病且为Ⅱ - Ⅲ级劳力性心绞痛功能分级的患者,单次静脉注射异搏定(10毫克)和奥昔利定(5毫克),以测试它们对血流动力学和冠状动脉血流参数的影响。在大多数情况下,发现给药后血流动力学和冠状动脉血流反应是相同的。得出的结论是,在正常动力性血流动力学中,异搏定作为抗心绞痛药物是有效的,而奥昔利定在高动力性血流动力学中有效。