Brown M S, Nelson S, Stewart B J
School of Nursing, Oregon Health Sciences University, Portland.
Nurse Pract. 1988 Oct;13(10):15-6, 18, 23-4.
This article reports two studies that replicate previous investigations of the effectiveness of Chemstrip bG, Dextrostix and Visidex for making nursing assessments of hypoglycemia in the newborn. The article also describes a third study that combines results of the first two studies with results of previous studies in the literature in an attempt to improve the reliability and validity of the findings. In the first study, 102 blood samples were tested using either Chemstrip bG or Dextrostix and then compared with laboratory blood glucose levels. Because of the small number of hypoglycemic samples, a second study was devised in which six samples of cord blood were artificially titrated to known levels of glucose. In this study, Visidex as well as Chemstrip bG and Dextrostix were used. Eighty-five percent, 50 percent and 90.4 percent of the hypoglycemic samples were detected by Chemstrip bG, Dextrostix and Visidex, respectively. Data available in the literature from previous studies investigating the same question were then compiled and analyzed. The composite sample of 402 infants for Dextrostix and 484 for Chemstrip bG resulted in the finding that less than half of the hypoglycemic infants tested with Dextrostix were detected whereas Chemstrip bG detected 90 percent of them. The conclusion reached is that both Chemstrip bG and Visidex can be considered adequate screening techniques for nursing assessment of hypoglycemia in the newborn, while visually read Dextrostix is unacceptable in clinical practice.
本文报道了两项研究，它们重复了先前关于Chemstrip bG、Dextrostix和Visidex在新生儿低血糖护理评估中有效性的调查。本文还描述了第三项研究，该研究将前两项研究的结果与文献中先前研究的结果相结合，试图提高研究结果的可靠性和有效性。在第一项研究中，使用Chemstrip bG或Dextrostix对102份血样进行检测，然后与实验室血糖水平进行比较。由于低血糖样本数量较少，因此设计了第二项研究，其中将六份脐带血样本人工滴定至已知的葡萄糖水平。在这项研究中，使用了Visidex以及Chemstrip bG和Dextrostix。Chemstrip bG、Dextrostix和Visidex分别检测出85%、50%和90.4%的低血糖样本。然后收集并分析了先前研究同一问题的文献中的可用数据。对Dextrostix的402名婴儿和Chemstrip bG的484名婴儿的综合样本进行分析后发现，使用Dextrostix检测的低血糖婴儿中，不到一半被检测出来，而Chemstrip bG检测出了其中的90%。得出的结论是，Chemstrip bG和Visidex都可被视为新生儿低血糖护理评估的适当筛查技术，而目视读取的Dextrostix在临床实践中不可接受。
