Wang Shunji, Ye Gaxi, Xu Chuanglong, Jia Aimin, Ru Yi, Guan Shuting, Ren Wenjing
Department of Acupuncture and Moxibustion, Ningxia Hui Autonomous Region Hospital of TCM, Yinchuan 750021, China.
Institute of TCM, Ningxia Medical University.
Zhongguo Zhen Jiu. 2018 Sep 12;38(9):919-24. doi: 10.13703/j.0255-2930.2018.09.003.
To observe the difference for vascular dementia among flipping moxibustion of medicine at acupoints in governor vessel combined with acupuncture, simple medicine and simple acupuncture.
A total of 120 patients with vascular dementia were randomly assigned into a combination group, a flipping moxibustion group and an acupuncture group, 40 cases in each one, with 2 patients dropping respectively. Flipping moxibustion was used at the acupoints of group A on Monday and at the acupoints of group B on Friday in the flipping moxibustion group. The acupoints of group A were Baihui (GV 20), Dazhui (GV 14), Shenzhu (GV 12), Zhiyang (GV 9), Jizhong (GV 6), Mingmen (GV 4), Yaoyangguan (GV 3), and the acupoints of group B were Fengfu (GV 16), Taodao (GV 13), Shendao (GV 11), Jinsuo (GV 8), Xuanshu (GV 5), Changqiang (GV 1). Acupuncture was used in the acupuncture group at the main acupoints of Baihui (GV 20), Sishencong (EX-HN 1), Neiguan (PC 6), Zusanli (ST 36), Taixi (KI 3) and Xuanzhong (GB 39), matched with the acupoints based on syndrome differentiation, 30 min a time, once a day, continuous 5 times a week. The above two methods were applied in the combination group. All the treaments were for 4 weeks. The indexes were observed before and after treatment, including syndrome differentiationof TCM scale for vascular dementia (SDSVD), simple mental state scale (MMSE), self-care ability of daily life scale (ADL). The clinical effects and safety were evaluated.
After treatment, the total effective rate in the combination group was 89.5% (34/38); the rate in the flipping moxibustion group was 65.8% (25/38); the rate in the acupuncture group was 63.2% (24/38). The difference among groups was statistically significant (<0.05). The effect in the combination group was better than those in the flipping moxibustion group and in the acupuncture group (both <0.05). There was no statistically significant difference between the flipping moxibustion group and the acupuncture group (>0.05). The SDSVD scores after treatment were lower and the MMSE and ADL scores after treatment were higher than those before treatment in the three groups (all <0.01), with better results on the above three scores in the combination group than those in the other two groups (<0.05, <0.01), and the differences on the three scores between the flipping moxibustion group and the acupuncture group were not statiatically significant (all >0.05). The treatment in the three groups was safe, without stastical significance (>0.05).
The effect of flipping moxibustion combined with acupuncture for vascular dementia is better than those of simple flipping moxibustion and simple acupuncture. The combination treatment achieves better effect on TCM syndrome, cognitive function and daily activity ability than the other two simple treatment.
观察督脉药物贴敷结合针刺、单纯药物贴敷、单纯针刺治疗血管性痴呆的差异。
将120例血管性痴呆患者随机分为联合组、药物贴敷组和针刺组,每组40例,每组各脱落2例。药物贴敷组周一在A组穴位进行贴敷,周五在B组穴位进行贴敷。A组穴位为百会(GV20)、大椎(GV14)、身柱(GV12)、至阳(GV9)、脊中(GV6)、命门(GV4)、腰阳关(GV3),B组穴位为风府(GV16)、陶道(GV13)、神道(GV11)、筋缩(GV8)、悬枢(GV5)、长强(GV1)。针刺组针刺百会(GV20)、四神聪(EX-HN1)、内关(PC6)、足三里(ST36)、太溪(KI3)、悬钟(GB39)为主穴,随证配穴,每次30分钟,每日1次,每周连续5次。联合组采用上述两种方法。所有治疗均持续4周。观察治疗前后血管性痴呆中医辨证量表(SDSVD)、简易精神状态量表(MMSE)、日常生活自理能力量表(ADL)等指标,评价临床疗效及安全性。
治疗后,联合组总有效率为89.5%(34/38);药物贴敷组为65.8%(25/38);针刺组为63.2%(24/38)。组间差异有统计学意义(<0.05)。联合组疗效优于药物贴敷组和针刺组(均<0.05)。药物贴敷组与针刺组比较差异无统计学意义(>0.05)。三组治疗后SDSVD评分均低于治疗前,MMSE及ADL评分均高于治疗前(均<0.01),联合组上述三项评分结果均优于其他两组(<0.05,<0.01),药物贴敷组与针刺组三项评分差异无统计学意义(均>0.05)。三组治疗均安全,差异无统计学意义(>0.05)。
督脉药物贴敷结合针刺治疗血管性痴呆的疗效优于单纯药物贴敷和单纯针刺。联合治疗在中医证候、认知功能及日常生活活动能力方面较其他两种单一治疗效果更佳。