Soares Jose Roberto Netto, Dias Fernando Luiz, Lima Roberto Rego Monteiro de Araujo, Toscano Ullyanov Bezerra, Pontes Ana Carolina Pastl, Botinelly Ruiter Diego, Souza Fernanda Gonzalez Rocha, Araujo Filho Vergilius José Furtado de, Matos Leandro Luongo, Cernea Claudio Roberto
. Head and Neck Surgery Service - National Cancer Institute, Rio de Janeiro/RJ, Brasil.
. Discipline of Head and Neck Surgery, Faculty of Medicine, University of São Paulo, São Paulo/SP, Brasil.
Rev Assoc Med Bras (1992). 2018 Aug;64(8):710-716. doi: 10.1590/1806-9282.64.08.710.
Malignant neoplasms of the head and neck, due to its anatomical location, can cause significant alterations in vital functions related to feeding, communication and social interaction of the affected patients.
To analyze the quality of life of patients with advanced malignant neoplasms of the oral cavity and submitted to radical operations with curative intent.
47 patients with oral cavity squamous cell carcinoma (SCC), in stages III and IV, underwent surgical treatment with segmental mandibulectomy and complementary radiotherapy. The patients were submitted to the quality of life questionnaires after a minimum time of six months after the surgical treatment.
Of the 183 patients, only 47 (25.7%) were able to answer the questionnaire and were included as the sample of the study. The majority of patients selected were male (39; 82.9%). The mean age was 64.4 years. The majority of the patients presented clinical stage IV (83%) and were submitted to adjuvant radiotherapy (95.4%). The mean score obtained after the questionnaires were applied was 64.6. The worst scores were found in swallowing and chewing.
There were no statistically significant differences in the domains of quality of life between the two groups studied (with bone reconstruction versus no bone reconstruction). Patients interviewed 2 years or more after treatment presented higher scores (p = 0.02).
头颈部恶性肿瘤因其解剖位置，可导致受影响患者与进食、交流和社交互动相关的重要功能发生显著改变。
分析口腔晚期恶性肿瘤患者接受根治性手术治疗后的生活质量。
47例Ⅲ期和Ⅳ期口腔鳞状细胞癌（SCC）患者接受了下颌骨节段性切除术及辅助放疗的手术治疗。患者在手术治疗后至少6个月接受生活质量问卷调查。
183例患者中，只有47例（25.7%）能够回答问卷并被纳入研究样本。所选患者大多数为男性（39例；82.9%）。平均年龄为64.4岁。大多数患者处于临床Ⅳ期（83%）并接受了辅助放疗（95.4%）。应用问卷后获得的平均分数为64.6。吞咽和咀嚼方面得分最差。
在研究的两组（有骨重建与无骨重建）之间，生活质量领域没有统计学上的显著差异。治疗后2年或更长时间接受访谈的患者得分更高（p = 0.02）。
