Department of Neurology, Northwell Health Hofstra School of Medicine, 300 Community Drive Manhasset, Manhasset, NY, 11030, USA.
Curr Pain Headache Rep. 2019 Jan 23;23(1):6. doi: 10.1007/s11916-019-0744-6.
Non-steroid anti-inflammatory drugs (NSAIDs) constitute a vital class of medications in today's headache regimen. However, up until the nineteenth century, they were largely unknown to most of the medical community. The purpose of this review is to explore the evolution of NSAIDs in the treatment of headaches spurred on by the Industrial Revolution in the USA.
The currently available data on the impact of NSAIDs reflects their significant contribution to headache treatment. The emergence of mass production spurred on by the Industrial Revolution, lead to widespread use of antipyrine, salicylic acid, and acetanilide. However, along with it came the growing awareness of consumer safety, leading to their ultimate downfall, and the subsequent birth of the Food and Drug Act.
非甾体抗炎药（NSAIDs）在当今头痛治疗方案中是一类重要的药物。然而，直到 19 世纪，它们在大多数医学界中还鲜为人知。本文旨在探讨美国工业革命推动下 NSAIDs 在头痛治疗中的演变。
目前关于 NSAIDs 影响的可用数据反映了它们对头痛治疗的重要贡献。工业革命带来的大规模生产的出现，促使了安替比林、水杨酸和乙酰苯胺的广泛使用。然而，随之而来的是对消费者安全意识的增强，导致了它们的最终衰落，并随后诞生了《食品和药品法》。
