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未分化型早期胃癌的内镜根治性切除术策略

Strategy for Curative Endoscopic Resection of Undifferentiated-Type Early Gastric Cancer.

作者信息

Kim Jie-Hyun

机构信息

Division of Gastroenterology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Clin Endosc. 2019 Jan;52(1):9-14. doi: 10.5946/ce.2018.199. Epub 2019 Jan 24.

DOI:10.5946/ce.2018.199
PMID:30674183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6370932/
Abstract

Endoscopic resection (ER) of undifferentiated-type early gastric cancer (UD-EGC) has a lower curative resection (CR) rate than differentiated-type EGC. However, if UD-EGC is curatively resected using ER, long-term outcomes can be favorable. Thus, the strategy for CR by ER is important in UD-EGC. To achieve CR in UD-EGC, biological behaviors including tumor growth patterns must be considered. This review aims to describe what is important for curative ER of UD-EGC.

摘要

未分化型早期胃癌（UD-EGC）的内镜切除术（ER）的根治性切除（CR）率低于分化型早期胃癌。然而，如果采用ER对UD-EGC进行根治性切除，长期预后可能良好。因此，ER实现CR的策略在UD-EGC中很重要。为了在UD-EGC中实现CR，必须考虑包括肿瘤生长模式在内的生物学行为。本综述旨在描述UD-EGC根治性ER的要点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/6370932/5e935184482f/ce-2018-199f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/6370932/1d874ec7902e/ce-2018-199f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/6370932/5e935184482f/ce-2018-199f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/6370932/1d874ec7902e/ce-2018-199f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/6370932/5e935184482f/ce-2018-199f2.jpg

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Risk Factors and Clinical Outcomes of Non-Curative Resection in Patients with Early Gastric Cancer Treated with Endoscopic Submucosal Dissection: A Retrospective Multicenter Study in Korea.内镜下黏膜下剥离术治疗早期胃癌患者非根治性切除的危险因素及临床结局：韩国一项回顾性多中心研究
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本文引用的文献

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Role of probe-based confocal laser endomicroscopy-targeted biopsy in the molecular and histopathological study of gastric cancer.探针式共聚焦激光显微内镜靶向活检在胃癌分子和组织病理学研究中的作用。
J Gastroenterol Hepatol. 2019 Jan;34(1):84-91. doi: 10.1111/jgh.14471. Epub 2018 Oct 4.
2
Undifferentiated-type component mixed with differentiated-type early gastric cancer is a significant risk factor for endoscopic non-curative resection.未分化型成分混合分化型早期胃癌是内镜非治愈性切除的一个显著危险因素。
Dig Endosc. 2018 Sep;30(5):624-632. doi: 10.1111/den.13059. Epub 2018 Apr 17.
3
Clinical predictors of histologic type of gastric cancer.
胃癌组织学类型的临床预测因子。
Gastrointest Endosc. 2018 Apr;87(4):1014-1022. doi: 10.1016/j.gie.2017.10.037. Epub 2017 Nov 6.
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Long-term outcomes of endoscopic submucosal dissection versus surgery in early gastric cancer meeting expanded indication including undifferentiated-type tumors: a criteria-based analysis.内镜黏膜下剥离术与手术治疗符合扩大适应证（包括未分化型肿瘤）的早期胃癌的长期疗效比较：基于标准的分析。
Gastric Cancer. 2018 May;21(3):490-499. doi: 10.1007/s10120-017-0772-z. Epub 2017 Oct 19.
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Endoscopic submucosal dissection for undifferentiated-type early gastric cancer: short- and long-term outcomes.内镜黏膜下剥离术治疗未分化型早期胃癌：短期和长期疗效。
Surg Endosc. 2018 Apr;32(4):1963-1970. doi: 10.1007/s00464-017-5892-3. Epub 2017 Oct 18.
6
The incidence of lymph node metastasis in early gastric cancer according to the expanded criteria in comparison with the absolute criteria of the Japanese Gastric Cancer Association: a systematic review of the literature and meta-analysis.基于日本胃癌协会的绝对标准与扩展标准比较，早期胃癌淋巴结转移的发生率：文献系统评价和荟萃分析。
Gastrointest Endosc. 2018 Feb;87(2):338-347. doi: 10.1016/j.gie.2017.09.025. Epub 2017 Sep 28.
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