Antifungal activity of oils macerates of North Sardinia plants against species isolated from clinical patients with candidiasis.

Antibiotic resistance is one of the problem of public health: the rise of multi-drug resistant organisms causes a challenge in the treatment of infective diseases. Anti-Candida resistance to conventional antifungal agents has increased in the last period. Our research was intended to evaluate antimicrobial activity of oil macerate (OM) of subsp and OM of subsp. against several clinical strains. The study included 30 patients with candidiasis who had not received any antifungal treatment before they were enrolled. A collection of 30 clinical isolates belonging to 5 different species of spp. was selected for this study. The data obtained showed an interesting activity of both Oil Macerate especially against and . On the contrary, Oil Macerate has had a better activity than the especially in relation to and .