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[孵育牛晶状体中还原型和氧化型谷胱甘肽含量的变化（作者译）]

[Changes in the content in reduced and oxydized glutathione in incubated bovine lenses (author's transl)].

作者信息

Hockwin O, Hata N

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 May 16;206(3):151-5. doi: 10.1007/BF00414740.

DOI:10.1007/BF00414740
PMID:306778
Abstract

Incubation of bovine lenses over a period of 24 h in Krebs-Ringer solution effects a decrease in the content of GSH. This decrease can be blocked by addition of 2 mM/1, each of glycine, glutamic acid, and cysteine. The content in GSSG is in no way influenced by incubation with or without addition of the three amino acids.

摘要

牛晶状体在 Krebs-Ringer 溶液中孵育 24 小时会导致谷胱甘肽（GSH）含量降低。添加 2 mM/1 的甘氨酸、谷氨酸和半胱氨酸中的每一种都可以阻止这种降低。无论是否添加这三种氨基酸进行孵育，氧化型谷胱甘肽（GSSG）的含量均不受影响。

相似文献

1
[Changes in the content in reduced and oxydized glutathione in incubated bovine lenses (author's transl)].[孵育牛晶状体中还原型和氧化型谷胱甘肽含量的变化（作者译）]
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 May 16;206(3):151-5. doi: 10.1007/BF00414740.
2
Is it possible to maintain a normal glutathione level in lenses in vitro?在体外能否维持晶状体中正常的谷胱甘肽水平？
Graefes Arch Clin Exp Ophthalmol. 1985;222(3):142-6. doi: 10.1007/BF02173539.
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[Changes in the content of glutathion and ascorbic acid in bovine lenses in dependence on age (author's transl)].
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The metabolism of amino acids in the bovine lens. Their oxidation as a source of energy.牛晶状体中氨基酸的代谢。它们作为能量来源的氧化过程。
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An HPLC radiotracer method for assessing the ability of L-cysteine prodrugs to maintain glutathione levels in the cultured rat lens.一种用于评估L-半胱氨酸前药维持培养大鼠晶状体中谷胱甘肽水平能力的高效液相色谱放射性示踪法。
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引用本文的文献

1
Superoxide dismutase (SOD) in normal and cataractous human lenses.
Graefes Arch Clin Exp Ophthalmol. 1984;222(2):79-81. doi: 10.1007/BF02150636.
2
Is it possible to maintain a normal glutathione level in lenses in vitro?在体外能否维持晶状体中正常的谷胱甘肽水平？
Graefes Arch Clin Exp Ophthalmol. 1985;222(3):142-6. doi: 10.1007/BF02173539.

本文引用的文献

1
Studies on the crystalline lens. IX. Quantitative analysis of free amino acids and related compounds.晶状体研究。IX. 游离氨基酸及相关化合物的定量分析。
Invest Ophthalmol. 1962 Oct;1:635-41.
2
[The effect of roentgen rays on the glutathione content of crystalline lens].
Med Exp Int J Exp Med. 1962;7:212-6.
3
Synthesis of glutathione by normal and x-irradiated lens.正常晶状体与经X射线照射的晶状体中谷胱甘肽的合成
Biochem J. 1955 Aug;60(4):xl.
4
Changes in lens during the formation of x-ray cataract in rabbits. II.兔X线白内障形成过程中晶状体的变化。II.
Biochem J. 1954 Mar;56(3):372-9. doi: 10.1042/bj0560372.
5
Studies on the crystalline lens. XII. Turnover of glycine and glutamic acid in glutathione and ophthalmic acid in the rabbit.晶状体研究。十二。兔体内谷胱甘肽和眼酸中甘氨酸和谷氨酸的周转情况。
Invest Ophthalmol. 1966 Dec;5(6):594-600.
6
Changes in the water, protein, and glutathione contents of the lens in the course of galactose cataract development in rats.大鼠半乳糖性白内障形成过程中晶状体水、蛋白质和谷胱甘肽含量的变化
Invest Ophthalmol. 1966 Dec;5(6):568-75.
7
Transport of L-glutamic acid and L-glutamine and their incorporation into lenticular glutathione.
Exp Eye Res. 1973 Dec 10;17(5):455-62. doi: 10.1016/0014-4835(73)90226-1.