Applebaum Jeremy, Harun Aisha, Davis Ashley, Hillel Alexander T, Best Simon R A, Akst Lee M
1 Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Ann Otol Rhinol Laryngol. 2019 May;128(5):384-390. doi: 10.1177/0003489419826133. Epub 2019 Jan 24.
An aging population has increased focus on geriatric otolaryngology. Those ≥65 years old are not a uniform population, however, and recent gerontology literature recognizes important physiologic differences between the young-old (ages 65-74 years), middle-old (75-84), and old-old (≥85). This study evaluates differences within these groups among dysphonia patients ≥65 years relative to diagnosis and voice-related quality of life (V-RQOL).
Chart review of all new patients ≥65 years presenting to the Johns Hopkins Voice Center between April 2015 and March 2017 identified chief complaint, diagnosis, and self-reported voice handicap. Etiology of dysphonia diagnoses were classified. Diagnostic categories and V-RQOL were evaluated as functions of patient age and gender.
Of 839 new patients ≥65 years, 463 (55.2%) reported chief complaint of dysphonia, with the most common etiologies being vocal fold immobility (28.3%) and atrophy (21.6%). Younger cohorts were more likely to present with benign vocal fold lesion and vocal fold immobility, while older cohorts were more likely to present with atrophy ( P = .016). The odds of having a diagnosis of vocal fold atrophy increased 7% with each year of life (odds ratio = 1.07; 95% CI, 1.03-1.11). V-RQOL scores were similar across gender and age categorization.
Dysphonia patients ≥65 years are not a uniform group, and important differences exist in terms of diagnosis as a function of age. Knowledge of these differences may inform further investigations in the growing field of geriatric otolaryngology.
人口老龄化使人们对老年耳鼻喉科的关注度增加。然而,65岁及以上的人群并非同质化群体,近期老年医学文献认识到年轻老年人(65 - 74岁)、中年老年人(75 - 84岁)和高龄老年人(≥85岁)之间存在重要的生理差异。本研究评估了65岁及以上的发音障碍患者在这些年龄组之间相对于诊断和与嗓音相关的生活质量(V - RQOL)的差异。
对2015年4月至2017年3月期间前往约翰·霍普金斯嗓音中心就诊的所有65岁及以上新患者的病历进行回顾,确定主要症状、诊断和自我报告的嗓音障碍情况。对发音障碍诊断的病因进行分类。将诊断类别和V - RQOL作为患者年龄和性别的函数进行评估。
在839名65岁及以上的新患者中,463名(55.2%)报告主要症状为发音障碍,最常见的病因是声带运动障碍(28.3%)和萎缩(21.6%)。较年轻的队列更易出现良性声带病变和声带运动障碍,而较年长的队列更易出现萎缩(P = 0.016)。年龄每增加一岁,诊断为声带萎缩的几率增加7%(比值比 = 1.07;95%置信区间,1.03 - 1.11)。V - RQOL评分在性别和年龄分类中相似。
65岁及以上的发音障碍患者并非同质化群体,在诊断方面存在随年龄变化的重要差异。了解这些差异可能为老年耳鼻喉科这一不断发展的领域的进一步研究提供参考。