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加拿大安大略省慢性轴性脊柱疼痛患者接受射频消融术后医疗服务利用情况及阿片类药物使用情况的回顾性队列研究。

Retrospective cohort study of healthcare utilization and opioid use following radiofrequency ablation for chronic axial spine pain in Ontario, Canada.

作者信息

Loh Eldon, Reid Jennifer N, Alibrahim Fatimah, Welk Blayne

机构信息

Department of Physical Medicine and Rehabilitation, Western University, London, Ontario, Canada

Parkwood Institute Research, Lawson Health Research Institute, London, Ontario, Canada.

出版信息

Reg Anesth Pain Med. 2019 Mar;44(3):398-405. doi: 10.1136/rapm-2018-100058. Epub 2019 Jan 23.

Abstract

BACKGROUND AND OBJECTIVES

Radiofrequency ablation (RFA) is a common treatment modality for chronic axial spine pain. Controversy exists over its effectiveness, and outcomes in a real-world setting have not been evaluated despite increasing use of RFA. This study examined changes in healthcare utilization and opioid use after RFA in Ontario, Canada.

METHODS

This retrospective cohort study was conducted in Ontario using administrative data. Ontario residents receiving their initial RFA between 1 January 2009 and 31 March 2015 were included. Physician visits, spinal injections, and opioid dosing/prescriptions in the 12-month periods before and after RFA were compared.

RESULTS

The study included 4653 patients. The number of RFA procedures significantly increased from 2009 to 2014 (22.5 cases/1 000 000 person-years to 82.5 cases/1 000 000 person-years). 4465 patients had at least one physician visit pre-RFA; there was a significant 23.89% reduction in physician visits post-RFA (pre-RFA: 29 616 visits; post-RFA: 22 542 visits). All reviewed specialties demonstrated a decrease in physician visits post-RF except neurosurgery. 3445 (85.70%) fewer spinal interventions for axial pain (medial/lateral branch blocks, facet/sacroiliac injections) were performed post-RFA. Significantly fewer epidurals were also performed post-RFA. 198 of 1007 patients (19.66%) on the Ontario Drug Benefit who received opioids pre-RFA did not require a postprocedure opioid prescription. Mean opioid dosing was unchanged post-RFA.

CONCLUSIONS

Healthcare utilization was significantly reduced in the 12 months following RFA, and some patients eliminated opioid use. Selection criteria for RFA are not standardized in Ontario, and appropriate use guidelines for spine interventions may improve outcomes and reduce unnecessary procedures.

摘要

背景与目的

射频消融术(RFA)是治疗慢性轴性脊柱疼痛的一种常用方法。关于其有效性存在争议,尽管RFA的使用越来越多,但尚未对其在实际临床中的疗效进行评估。本研究调查了加拿大安大略省患者接受RFA治疗后医疗资源利用情况和阿片类药物使用的变化。

方法

本回顾性队列研究利用安大略省的管理数据进行。纳入2009年1月1日至2015年3月31日期间首次接受RFA治疗的安大略省居民。比较RFA治疗前后12个月内的门诊就诊、脊柱注射以及阿片类药物剂量/处方情况。

结果

该研究共纳入4653例患者。2009年至2014年,RFA手术数量显著增加(从22.5例/100万人年增至82.5例/100万人年)。4465例患者在RFA治疗前至少有一次门诊就诊;RFA治疗后门诊就诊次数显著减少23.89%(RFA治疗前:29616次就诊;RFA治疗后:22542次就诊)。除神经外科外,所有纳入评估的专科在RFA治疗后的门诊就诊次数均有所减少。RFA治疗后,针对轴性疼痛的脊柱干预措施(内侧/外侧支阻滞、小关节/骶髂关节注射)减少了3445例(85.70%)。RFA治疗后硬膜外注射的次数也显著减少。在安大略省药物福利计划中,1007例RFA治疗前使用阿片类药物的患者中有198例(19.66%)在治疗后无需开具阿片类药物处方。RFA治疗后阿片类药物的平均剂量未发生变化。

结论

RFA治疗后的12个月内,医疗资源利用显著减少,部分患者不再使用阿片类药物。安大略省RFA的选择标准尚未标准化,制定脊柱干预措施的合理使用指南可能会改善治疗效果并减少不必要的手术。

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