金催化的乙烯环丙烷化反应。

Gold-catalyzed ethylene cyclopropanation.

作者信息

Rull Silvia G, Olmos Andrea, Pérez Pedro J

机构信息

Laboratorio de Catálisis Homogénea, Unidad Asociada al CSIC, CIQSO-Centro de Investigación en Química Sostenible and Departamento de Química, Universidad de Huelva, Campus de El Carmen 21007 Huelva, Spain.

出版信息

Beilstein J Org Chem. 2019 Jan 7;15:67-71. doi: 10.3762/bjoc.15.7. eCollection 2019.

DOI:10.3762/bjoc.15.7

PMID:30680040

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6334794/

Abstract

Ethylene can be directly converted into ethyl 1-cyclopropylcarboxylate upon reaction with ethyl diazoacetate (NCHCOEt, EDA) in the presence of catalytic amounts of IPrAuCl/NaBAr (IPr = 1,3-bis(2,6-diisopropylphenyl)imidazole-2-ylidene; BAr = tetrakis(3,5-bis(trifluoromethyl)phenyl)borate).

摘要

在催化量的IPrAuCl/NaBAr（IPr = 1,3 - 双（2,6 - 二异丙基苯基）咪唑 - 2 - 亚基；BAr = 四（3,5 - 双（三氟甲基）苯基）硼酸酯）存在下，乙烯与重氮乙酸乙酯（NCHCOEt，EDA）反应时可直接转化为1 - 环丙基甲酸乙酯。