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Inhibiting microcephaly genes as alternative to microtubule targeting agents to treat brain tumors.抑制小头畸形基因作为治疗脑肿瘤的微管靶向药物的替代物。
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Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.巢蛋白对于神经胶质瘤细胞中纺锤体的组装和细胞周期的进展是必需的。
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Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer.取代喹唑啉类化合物在癌症治疗中与多个靶点相互作用的潜力。
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本文引用的文献

1
Trial Watch: Glioblastoma vaccine therapy disappointment in Phase III trial.试验观察:胶质母细胞瘤疫苗疗法在III期试验中令人失望。
Nat Rev Neurol. 2016 Apr;12(4):190. doi: 10.1038/nrneurol.2016.38. Epub 2016 Mar 29.
2
Overview of current immunotherapeutic strategies for glioma.胶质瘤当前免疫治疗策略概述
Immunotherapy. 2015;7(10):1073-104. doi: 10.2217/imt.15.75.
3
CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012.CBTRUS统计报告:2008 - 2012年美国原发性脑和中枢神经系统肿瘤诊断情况
Neuro Oncol. 2015 Oct;17 Suppl 4(Suppl 4):iv1-iv62. doi: 10.1093/neuonc/nov189. Epub 2015 Oct 27.
4
Neurodegeneration and microtubule dynamics: death by a thousand cuts.神经退行性变与微管动力学:千刀万剐式死亡
Front Cell Neurosci. 2015 Sep 9;9:343. doi: 10.3389/fncel.2015.00343. eCollection 2015.
5
Synthesis, Characterization, and Bioactivity of the Photoisomerizable Tubulin Polymerization Inhibitor azo-Combretastatin A4.光致异构化微管聚合抑制剂氮杂康普瑞汀 A4 的合成、表征及生物活性
Org Lett. 2015 Sep 18;17(18):4546-9. doi: 10.1021/acs.orglett.5b02262. Epub 2015 Sep 3.
6
A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model.一种新型抗胶质瘤疗法AG119:在小鼠GL261胶质瘤模型中的临床前评估
BMC Cancer. 2015 Jul 17;15:522. doi: 10.1186/s12885-015-1538-9.
7
Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death.光控微管动力学抑制剂对有丝分裂和细胞死亡的光学控制
Cell. 2015 Jul 16;162(2):403-411. doi: 10.1016/j.cell.2015.06.049. Epub 2015 Jul 9.
8
IsoCombretaQuinazolines: Potent Cytotoxic Agents with Antitubulin Activity.异康布雷他喹唑啉类:具有抗微管蛋白活性的强效细胞毒剂。
ChemMedChem. 2015 Aug;10(8):1392-402. doi: 10.1002/cmdc.201500069. Epub 2015 Jun 15.
9
Emerging microtubule targets in glioma therapy.胶质瘤治疗中新兴的微管靶点
Semin Pediatr Neurol. 2015 Mar;22(1):49-72. doi: 10.1016/j.spen.2015.03.009. Epub 2015 Apr 4.
10
Immunotherapy for primary brain tumors: no longer a matter of privilege.原发性脑肿瘤的免疫疗法:不再是特权问题。
Clin Cancer Res. 2014 Nov 15;20(22):5620-9. doi: 10.1158/1078-0432.CCR-14-0832.

Microtubule targeting agents in glioma.

作者信息

Calinescu Anda-Alexandra, Castro Maria G

机构信息

Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI, USA.

Department of Cellular and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.

出版信息

Transl Cancer Res. 2016 Jun;5(Suppl 1):S54-S60. doi: 10.21037/tcr.2016.06.12.

DOI:10.21037/tcr.2016.06.12
PMID:30680290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6342473/
Abstract
摘要