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大动脉转位且室间隔完整时左心室训练的更好方法:双向腔肺吻合术和肺动脉环扎术。

A better approach for left ventricular training in transposition of the great arteries and intact interventricular septum: Bidirectional cavopulmonary anastomosis and pulmonary artery banding.

作者信息

Bilal Mehmet Salih, Özyüksel Arda, Kemal Avşar Mustafa, Demiroluk Şener, Küçükosmanoğlu Osman, Yalçın Yalım

机构信息

Department of Cardiovascular Surgery, Medicana International Hospital, Istanbul, Turkey.

Department of Cardiovascular Surgery, Biruni University, Istanbul, Turkey.

出版信息

Congenit Heart Dis. 2019 May;14(3):464-469. doi: 10.1111/chd.12749. Epub 2019 Jan 25.

Abstract

OBJECTIVE

Management of the patients with transposition of the great arteries and intact ventricular septum may be challenging beyond the newborn period. Herein, we would like to present our alternative strategy for training the left ventricle in these patients.

METHODS

Six patients with transposition of the great arteries and intact ventricular septum were evaluated in our clinic. Two of them were palliated with Glenn procedure and pulmonary banding as a definitive treatment strategy at other centers. Four patients were operated on and a bidirectional cavopulmonary anastomosis in combination with pulmonary artery banding was performed (stage-1: palliation and ventricular training) in our center. In four out of these six patients, arterial switch operation was performed with takedown and direct re-anastomosis of the superior vena cava to right atrium after an interstage period of 21-30 months (stage-2: anatomical repair).

RESULTS

Any mortality was not encountered. The left ventricular mass indices increased from 18-32 to 44-74 g/m in patients undergoing the anatomical repair. All of the patients were uneventfully discharged following the second stage. The mean follow-up period was 20 months (9-32 months) following stage 2. All of the patients are doing well with trivial neoaortic regurgitation and normal biventricular function.

CONCLUSIONS

Bidirectional cavopulmonary anastomosis with pulmonary artery banding may be a promising left ventricle training approach in ventriculoarterial discordance when compared to the traditional pulmonary artery banding with concomitant systemic-to-pulmonary artery shunt procedures which still carry a significant interstage morbidity and mortality.

摘要

目的

对于大动脉转位且室间隔完整的患者,新生儿期后的管理可能具有挑战性。在此,我们想介绍我们在这些患者中训练左心室的替代策略。

方法

我们诊所评估了6例大动脉转位且室间隔完整的患者。其中2例在其他中心接受了格林手术和肺动脉环扎术作为确定性治疗策略。4例患者在我们中心接受了手术,进行了双向腔肺吻合术并结合肺动脉环扎术(第1阶段:姑息治疗和心室训练)。在这6例患者中的4例中,在21至30个月的中间阶段后,进行了动脉调转手术,同时将上腔静脉向下游离并直接重新吻合至右心房(第2阶段:解剖修复)。

结果

未发生任何死亡。接受解剖修复的患者左心室质量指数从18 - 32 g/m增加到44 - 74 g/m。所有患者在第二阶段后均顺利出院。第二阶段后的平均随访期为20个月(9 - 32个月)。所有患者情况良好,仅有轻微的新主动脉瓣反流,双心室功能正常。

结论

与传统的肺动脉环扎术及同期体肺分流手术相比,双向腔肺吻合术联合肺动脉环扎术可能是一种在心室动脉不一致情况下训练左心室的有前景的方法,传统方法仍存在显著的中间阶段发病率和死亡率。

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