Ma Kai, Qi Lei, Hua Zhongdong, Yang Keming, Zhang Hao, Li Shoujun, Zhang Sen, He Fengpu, Wang Guanxi
Tex Heart Inst J. 2020 Feb 1;47(1):15-22. doi: 10.14503/THIJ-17-6555. eCollection 2020 Feb.
Surgery for complex congenitally corrected transposed great arteries is one of the greatest challenges in cardiovascular surgery. We report our experience with bidirectional Glenn shunt placement as a palliative procedure for complex congenitally corrected transposition. We retrospectively identified 50 consecutive patients who had been diagnosed with congenitally corrected transposition accompanied by left ventricular outflow tract obstruction and ventricular septal defect and who had then undergone palliative bidirectional Glenn shunt placement at our institution from January 2005 through December 2014. Patients were divided into 3 groups according to subsequent surgeries: Fontan completion (total cavopulmonary connection, 13 patients) (group 1), anatomic repair (hemi-Mustard and Rastelli procedures without Glenn takedown, 11 patients) (group 2), and prolonged palliation (no further surgery, 26 patients) (group 3). After shunt placement, no patient died or had ventricular dysfunction. Overall, mean oxygen saturation increased significantly from 79.5% ± 13.5% preoperatively to 94.1% ± 7.3% ( <0.001). The median time from shunt placement to Fontan completion and anatomic repair, respectively, was 2.1 years (range, 1.6-5.2 yr) and 1.1 years (range, 0.6-2.4 yr). Only 2 late deaths occurred, both in group 1. In group 3, time from shunt placement to latest follow-up was 4.5 years (range, 2.3-8 yr). At latest follow-up, mean oxygen saturation was 91.6% ± 10.3%, and no patients had impaired ventricular function. Bidirectional Glenn shunt placement as an optional palliative procedure for complex congenitally corrected transposition has favorable outcomes. Later, patients can feasibly be treated by Fontan completion or anatomic repair. Use of a bidirectional Glenn shunt for open-ended palliation is also acceptable.
复杂型先天性矫正型大动脉转位的手术是心血管外科领域最具挑战性的手术之一。我们报告了我们将双向格林分流术作为复杂型先天性矫正型大动脉转位姑息性手术的经验。我们回顾性地确定了50例连续患者,这些患者被诊断为先天性矫正型大动脉转位并伴有左心室流出道梗阻和室间隔缺损,于2005年1月至2014年12月在我们机构接受了姑息性双向格林分流术。根据后续手术情况将患者分为3组:Fontan完成术(全腔静脉肺动脉连接术,13例患者)(第1组)、解剖修复术(半Mustard术和Rastelli术且未拆除格林分流,11例患者)(第2组)以及长期姑息治疗(未进一步手术,26例患者)(第3组)。分流术后,无患者死亡或出现心室功能障碍。总体而言,平均血氧饱和度从术前的79.5%±13.5%显著提高至94.1%±7.3%(<0.001)。从分流术至Fontan完成术和解剖修复术的中位时间分别为2.1年(范围1.6 - 5.2年)和1.1年(范围0.6 - 2.4年)。仅发生2例晚期死亡,均在第1组。在第3组,从分流术至最近一次随访的时间为4.5年(范围2.3 - 8年)。在最近一次随访时,平均血氧饱和度为91.6%±10.3%,且无患者心室功能受损。双向格林分流术作为复杂型先天性矫正型大动脉转位的一种可选姑息性手术具有良好的效果。之后,患者可通过Fontan完成术或解剖修复术进行合理治疗。使用双向格林分流术进行开放式姑息治疗也是可以接受的。