药代动力学/药效学（PK/PD）联合建模
Combined pharmacokinetic/pharmacodynamic (PK/PD) modeling.
作者信息
Colburn W A
机构信息
Pharmacokinetics/Drug Metabolism Department, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, Michigan 48105.
出版信息
J Clin Pharmacol. 1988 Sep;28(9):769-71. doi: 10.1002/j.1552-4604.1988.tb03215.x.
Abstract
Several compartmental and noncompartmental approaches have been successfully applied to PK/PD modeling. Although great opportunities exist to expand on these techniques, application of these methods to relate concentrations of all drugs to their effects is possible.
摘要
几种房室和非房室方法已成功应用于药代动力学/药效学（PK/PD）建模。尽管在扩展这些技术方面存在巨大机遇，但将这些方法应用于关联所有药物的浓度与其效应是可行的。
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