Medicine Service, Birmingham VA Medical Center, Birmingham, AL, UK.
Department of Epidemiology at the School of Public Health, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Arthritis Res Ther. 2019 Jan 25;21(1):36. doi: 10.1186/s13075-019-1821-2.
Limited information exists regarding sleep disorders in gout. Our objective was to assess the burden of sleep disorders in people with gout.
A brief anonymized Internet survey of people with physician-diagnosed gout who visited a gout education website assessed the frequency of sleep problems, sleep quality over the past 24 h (0 = best possible sleep, 10 = worst possible sleep), daytime sleepiness on a typical day (0 = none and 10 = most sleepy during the day), sleep quantity (number of hours of sleep), and the frequency of snoring or gasping, and snorting or stopping breathing during the sleep, using validated questionnaires, including the NHANES 2016 sleep questionnaire. We used Chi-square test to compare the categorical and t test the continuous variables.
Of the 454 website visitors who clicked the survey, 320 survey respondents reported physician-diagnosed gout. Mean age was 57 years (standard deviation [SD], 13.4), 72% were male, 77% were White, and mean gout duration was 7.6 (SD, 11). Of the respondents, 23% reported doctor-diagnosed sleep disorder (sleep apnea, 17%; sleep study ordered, diagnosis pending, 4%; other sleep disorder 2%). A mean 6.7 h of sleep per night was reported (SD, 1.3). Eighty-six percent reported snoring during sleep and 45% reported having snorted, gasped, or stopped breathing while asleep. Two thirds of the patients reported feeling sleepy during the day, at least 3-4 times a month or more. Sleep quality was 5.5 (SD, 2.6), and daytime sleepiness was 3.5 (SD, 2.6) on a 0-10 scale (higher = worse).
People with physician-diagnosed gout reported frequent sleep disorders and daytime sleepiness in an Internet survey. More in-depth studies are needed to better understand the association of gout with sleep disorders.
关于痛风患者的睡眠障碍，相关信息有限。我们的目的是评估痛风患者的睡眠障碍负担。
一项针对在痛风教育网站就诊的痛风患者的简短匿名互联网调查，评估了睡眠问题的频率、过去 24 小时的睡眠质量（0=最佳睡眠，10=最差睡眠）、典型日的日间嗜睡（0=无，10=白天最困倦）、睡眠量（睡眠时间），以及打鼾或喘气、鼻息或呼吸暂停的频率，使用验证过的问卷，包括 NHANES 2016 睡眠问卷。我们使用卡方检验比较分类变量，t 检验比较连续变量。
在点击调查的 454 名网站访问者中，有 320 名调查受访者报告了医生诊断的痛风。平均年龄为 57 岁（标准差[SD]，13.4），72%为男性，77%为白人，痛风平均病程为 7.6 年（SD，11 年）。在受访者中，23%报告了医生诊断的睡眠障碍（睡眠呼吸暂停，17%；睡眠研究已安排，待诊断，4%；其他睡眠障碍，2%）。每晚报告的平均睡眠时间为 6.7 小时（SD，1.3 小时）。86%的人报告在睡眠中打鼾，45%的人报告在睡眠中鼻息、喘气或呼吸暂停。三分之二的患者报告至少每月有 3-4 次或更多次白天感到困倦。睡眠质量为 5.5（SD，2.6），日间嗜睡程度为 3.5（SD，2.6），评分范围为 0-10（分数越高表示睡眠质量越差）。
在互联网调查中，患有痛风的患者报告了频繁的睡眠障碍和白天嗜睡。需要更深入的研究来更好地了解痛风与睡眠障碍之间的关联。
