Department of Human Health Sciences,Graduate School of Medicine Kyoto University,Kyoto,Japan.
Department of Nursing,Kyoto University Hospital,Kyoto,Japan.
Palliat Support Care. 2019 Feb;17(1):46-53. doi: 10.1017/S1478951518000901. Epub 2019 Jan 26.
To obtain preliminary knowledge to design a randomized controlled trial to clarify the effects of spiritual care using the Spiritual Pain Assessment Sheet (SpiPas).
The study was designed as a nonrandomized controlled trial. The study took place between January 2015 and July 2015 in a hematology and oncology ward and two palliative care units in Japan. Among 54 eligible patients with advanced cancer, 46 were recruited (24 in the control group vs. 22 in the intervention group). The intervention group received spiritual care using SpiPas and usual care; the control group received usual care. The primary outcome was the Functional Assessment of Chronic Illness Therapy-Spiritual (FACIT-Sp). The secondary outcomes were the Hospital Anxiety and Depression Scale (HADS) and Comprehensive Quality of Life Outcome (CoQoLo).ResultA total of 33 (72%) and 23 (50%) patients completed 2- and 3-week follow-up evaluations, respectively. The differences in the changes during 2 weeks in total scores of FACIT-Sp and HADS were significant (95% confidence intervals, 3.65, 14.4, p < 0.01; -11.2 to -1.09, p = .02, respectively). No significant changes were observed in the total score of CoQoLo.Significance of resultsSpiritual care using the SpiPas might be useful for improving patient spiritual well-being. This controlled clinical trial could be performed and a future clinical trial is promising if outcomes are obtained within 2 weeks.
获得设计一项随机对照试验的初步知识，以明确使用精神痛苦评估表（SpiPas）进行精神关怀的效果。
本研究设计为非随机对照试验。研究于 2015 年 1 月至 7 月在日本的一个血液科和肿瘤科病房和两个姑息治疗单位进行。在 54 名符合条件的晚期癌症患者中，有 46 名患者入组（对照组 24 名，干预组 22 名）。干预组接受 SpiPas 精神关怀和常规护理；对照组接受常规护理。主要结局是慢性疾病治疗的功能性评估-精神（FACIT-Sp）。次要结局是医院焦虑和抑郁量表（HADS）和综合生活质量结局（CoQoLo）。
共有 33 名（72%）和 23 名（50%）患者分别完成了 2 周和 3 周的随访评估。2 周内 FACIT-Sp 和 HADS 总分变化的差异具有统计学意义（95%置信区间，3.65，14.4，p < 0.01；-11.2 至-1.09，p =.02）。CoQoLo 的总分没有观察到显著变化。
使用 SpiPas 的精神关怀可能有助于改善患者的精神幸福感。如果在 2 周内获得结果，该对照临床试验可以进行，未来的临床试验也很有希望。
