Department of Materials Processing, Tohoku University, 6-6-02 Aza Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579, Japan.
Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
J Biomed Mater Res A. 2019 May;107(5):991-1000. doi: 10.1002/jbm.a.36624. Epub 2019 Feb 19.
Rutile TiO layers were formed on substrates of Ti-(0-10)at%Au alloys by a simple process of air oxidation, and their antibacterial activities were evaluated under visible-light irradiation (λ ≥ 400 nm). Au was introduced into the TiO layers on Ti-(1-10)at%Au alloys and existed as both metallic Au nanoparticles and dissolved Au ions. The TiO layers that formed on Ti-5at%Au and Ti-10at%Au alloys exhibited visible-light photocatalytic activity, that is, degradation of stearic acid and antibacterial activity against Escherichia coli. These visible-light activities were attributed to the surface plasmon resonance of metallic Au nanoparticles and the decrease in bandgap energy caused by dissolved Au ions. The formation of hydroxyl radicals observed under visible-light irradiation is attributable to antibacterial activity. From a cost perspective, a Ti-5at%Au alloy is more suitable as a substrate for the formation of a TiO layer with antibacterial properties than a Ti-10at%Au alloy. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 107A: 991-1000, 2019.
通过简单的空气氧化过程，在 Ti-(0-10)at%Au 合金基底上形成了锐钛矿 TiO 层，并在可见光照射（λ≥400nm）下评估了它们的抗菌活性。Au 被引入到 Ti-(1-10)at%Au 合金的 TiO 层中，存在于金属 Au 纳米粒子和溶解的 Au 离子中。在 Ti-5at%Au 和 Ti-10at%Au 合金上形成的 TiO 层表现出可见光光催化活性，即硬脂酸的降解和对大肠杆菌的抗菌活性。这些可见光活性归因于金属 Au 纳米粒子的表面等离子体共振和溶解的 Au 离子引起的能带隙能量降低。在可见光照射下观察到的羟基自由基的形成归因于抗菌活性。从成本角度来看，与 Ti-10at%Au 合金相比，Ti-5at%Au 合金更适合作为形成具有抗菌性能的 TiO 层的基底。©2019Wiley Periodicals，Inc. J Biomed Mater Res Part A：107A：991-1000，2019。
