Moon Kyoung-Suk, Park Young-Bum, Bae Ji-Myung, Choi Eun-Joo, Oh Seung-Han
Department of Dental Biomaterials, The Institute of Biomaterial and Implant, School of Dentistry, Wonkwang University, Iksan 54538, Korea.
Department of Prosthodontics, School of Dentistry, Yonsei University, Seoul 03722, Korea.
Materials (Basel). 2021 Oct 11;14(20):5976. doi: 10.3390/ma14205976.
The visible light reactions of noble metal-based photocatalysts have been increasingly utilized to investigate their antibacterial activities. Furthermore, the photoreactions at various visible light wavelengths for specific combinations of titania nanotubes and noble metal nanoparticles have been found to promote osteogenic functionality. In this investigation, a novel multi-coating combination of noble metals (gold and platinum) on titania nanotubes was assessed using plasmonic photocatalysis and low-level laser therapy at 470 and 600 nm. The results showed that this coating on the nanotubes promoted antibacterial activity and osteogenic functionality. The order in which the gold and platinum coatings were layered onto the titania nanotubes strongly affected the osteogenic performance of the human mesenchymal stem cells. These results have identified a new approach for the development of efficient novel combinations of noble metal nanoparticles and titania nanotubes with visible light responses, sustainable antimicrobial activity, and osteogenic functionality.
基于贵金属的光催化剂的可见光反应已越来越多地用于研究其抗菌活性。此外，已发现二氧化钛纳米管与贵金属纳米颗粒的特定组合在各种可见光波长下的光反应可促进成骨功能。在本研究中，使用等离子体光催化和470和600nm的低强度激光疗法评估了二氧化钛纳米管上贵金属（金和铂）的新型多层涂层组合。结果表明，纳米管上的这种涂层促进了抗菌活性和成骨功能。金和铂涂层沉积在二氧化钛纳米管上的顺序强烈影响人间充质干细胞的成骨性能。这些结果确定了一种开发具有可见光响应、可持续抗菌活性和成骨功能的贵金属纳米颗粒与二氧化钛纳米管高效新型组合的新方法。
