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社区获得性嗜麦芽寡养单胞菌 discitis:宏基因组测序辅助诊断。

Community acquired Stenotrophomonas maltophilia discitis: Diagnosis aided by shotgun metagenomic sequencing.

机构信息

Department of Infectious Diseases, Qilu Hospital, Shandong University, Jinan, Shandong, China.

Department of Infectious Diseases, Qilu Hospital, Shandong University, Jinan, Shandong, China.

出版信息

Int J Infect Dis. 2019 Apr;81:1-3. doi: 10.1016/j.ijid.2019.01.032. Epub 2019 Jan 23.

DOI:10.1016/j.ijid.2019.01.032
PMID:30684744
Abstract

We report a rare case of culture negative L4-L5 discitis and epidural abscess in an immunocompetent child who had dry cupping therapy performed to treat low back strain. The causative pathogen was identified as Stenotrophomonas maltophilia by shotgun metagenomic sequencing of spinal cord aspirate after more than one month of unsuccessful empirical treatment with 6 different antibiotics. The patient was successfully treated with Sulfamethoxazole-trimethoprim and minocycline. Cupping therapy is a very popular medical procedure widely used in China, but the potential risk for severe infections such as discitis and epidural abscess described in this case should be recognized.

摘要

我们报告了一例罕见的免疫功能正常的儿童 L4-L5 椎间盘炎和硬膜外脓肿病例,该患儿因腰部劳损接受干拔罐治疗。在经过 6 种不同抗生素的经验性治疗一个多月后仍未成功,通过对脊髓吸出物进行鸟枪法宏基因组测序,确定病原体为嗜麦芽寡养单胞菌。该患者经磺胺甲噁唑-甲氧苄啶和米诺环素治疗后痊愈。拔罐疗法在中国是一种非常流行的医疗程序,但正如本例所述,其存在引发椎间盘炎和硬膜外脓肿等严重感染的潜在风险,应该引起重视。

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