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锁骨骨折与臂丛神经产瘫的关联

The Association of Clavicle Fracture With Brachial Plexus Birth Palsy.

作者信息

Gandhi Rikesh A, DeFrancesco Christopher J, Shah Apurva S

机构信息

Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA.

Division of Orthopaedics, Children's Hospital of Philadelphia, Philadelphia, PA.

出版信息

J Hand Surg Am. 2019 Jun;44(6):467-472. doi: 10.1016/j.jhsa.2018.11.006. Epub 2019 Jan 23.

Abstract

PURPOSE

Shoulder dystocia is the strongest known risk factor for brachial plexus birth palsy (BPBP). Fractures of the clavicle are known to occur in the setting of shoulder dystocia. It remains unknown whether a clavicle fracture that occurs during a birth delivery with shoulder dystocia increases the risk of BPBP or, alternatively, is protective. The purpose of this study was to use a large, national database to determine whether a clavicle fracture in the setting of shoulder dystocia is associated with an increased or decreased risk of BPBP.

MATERIALS AND METHODS

The 1997 to 2012 Kids' Inpatient Database (KID) was analyzed for this study. International Classification of Diseases, Ninth Revision (ICD-9) codes were used to identify newborns diagnosed with shoulder dystocia and BPBP as well as a concurrent fracture of the clavicle. Newborns with shoulder dystocia were stratified into 2 groups: dystocia without a clavicle fracture and dystocia with a clavicle fracture. Multivariable logistic regression was used to quantify the risk for BPBP among shoulder dystocia subgroups.

RESULTS

The dataset included 5,564,628 sample births extrapolated to 23,385,597 population births over the 16-year study period. A BPBP occurred at a rate of 1.2 per 1,000 births. Shoulder dystocia complicated 18.8% of births with a BPBP. A total of 7.84% of newborns with a BPBP also sustained a clavicle fracture. Births with shoulder dystocia and a clavicle fracture incurred BPBP at a rate similar to that for newborns with shoulder dystocia and no fracture (9.82% vs 11.77%). Shoulder dystocia without a concurrent clavicle fracture was an independent risk factor for BPBP (odds ratio, 112.1; 95% confidence interval, 103.5-121.4). Those with shoulder dystocia and clavicle fracture had a risk for BPBP comparable with those with shoulder dystocia but no fracture (odds ratio, 126.7 vs 112.1).

CONCLUSIONS

This population-level investigation suggests that, among newborns with shoulder dystocia, clavicle fracture is not associated with a significant change in the risk of BPBP.

TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic II.

摘要

目的

肩难产是已知的臂丛神经产瘫(BPBP)最强风险因素。已知锁骨骨折发生在肩难产的情况下。尚不清楚在伴有肩难产的分娩过程中发生的锁骨骨折是会增加BPBP的风险,还是具有保护作用。本研究的目的是使用一个大型的全国性数据库来确定肩难产情况下的锁骨骨折与BPBP风险增加或降低是否相关。

材料与方法

本研究分析了1997年至2012年的儿童住院数据库(KID)。使用国际疾病分类第九版(ICD-9)编码来识别诊断为肩难产和BPBP以及并发锁骨骨折的新生儿。将患有肩难产的新生儿分为两组:无锁骨骨折的难产组和有锁骨骨折的难产组。采用多变量逻辑回归来量化肩难产亚组中BPBP的风险。

结果

在16年的研究期间,数据集包括5564628例样本出生,推算为23385597例总体出生。BPBP的发生率为每1000例出生中有1.2例。肩难产使18.8%的BPBP分娩复杂化。共有7.84%的BPBP新生儿也发生了锁骨骨折。伴有肩难产和锁骨骨折的新生儿发生BPBP的比率与伴有肩难产但无骨折的新生儿相似(9.82%对11.77%)。无并发锁骨骨折的肩难产是BPBP的独立风险因素(比值比,112.1;95%置信区间,103.5 - 121.4)。伴有肩难产和锁骨骨折的新生儿发生BPBP的风险与伴有肩难产但无骨折的新生儿相当(比值比,126.7对112.1)。

结论

这项基于人群的调查表明,在患有肩难产的新生儿中,锁骨骨折与BPBP风险的显著变化无关。

研究类型/证据水平:预后性研究II级。

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