Zarbin M A, Michels R G, de Bustros S, Quigley H A, Patel A
Wilmer Ophthalmological Institute, Johns Hopkins Hospital, Baltimore.
Ophthalmology. 1988 Dec;95(12):1639-48. doi: 10.1016/s0161-6420(88)32963-5.
Endolaser photocoagulation of the ciliary body was used to treat 42 eyes with severe glaucoma that could not be managed successfully by medical therapy and conventional glaucoma surgery. Follow-up ranged from 6 to 36 months (mean, 13 months). The preoperative intraocular pressure (IOP) ranged from 13 to 76 mmHg (mean, 37 mmHg). The postoperative IOP ranged from 1 to 44 mmHg (mean, 17 mmHg), representing an absolute decrease of 20 mmHg, and a mean decrease of 48%. After one or two (7 eyes) treatment sessions, 11 eyes (26%) had an IOP less than 21 mmHg without medications; 21 eyes (50%) had an IOP less than 21 mmHg with medications; 5 eyes (12%) had an IOP of 21 to 25 mmHg with or without medications; and 5 eyes (12%) had an IOP greater than 25 mmHg. Postoperatively, the number of antiglaucoma medications required was reduced from a mean of 2.8 +/- 0.13 to a mean of 1.4 +/- 0.19. Twenty-three (72%) of 32 patients were able to discontinue carbonic anhydrase inhibitors.
采用睫状体激光光凝术治疗42例药物治疗和传统青光眼手术无法成功控制的重度青光眼患者。随访时间为6至36个月（平均13个月）。术前眼压范围为13至76 mmHg（平均37 mmHg）。术后眼压范围为1至44 mmHg（平均17 mmHg），绝对降低20 mmHg，平均降低48%。经过一或两个疗程（7只眼）的治疗后，11只眼（26%）在未使用药物的情况下眼压低于21 mmHg；21只眼（50%）在使用药物的情况下眼压低于21 mmHg；5只眼（12%）无论是否使用药物眼压在21至25 mmHg之间；5只眼（12%）眼压高于25 mmHg。术后，所需抗青光眼药物的数量从平均2.8±0.13减少到平均1.4±0.19。32例患者中有23例（72%）能够停用碳酸酐酶抑制剂。
