激光睫状体光凝术治疗重度青光眼。

Endolaser treatment of the ciliary body for severe glaucoma.

作者信息

Zarbin M A, Michels R G, de Bustros S, Quigley H A, Patel A

机构信息

Wilmer Ophthalmological Institute, Johns Hopkins Hospital, Baltimore.

出版信息

Ophthalmology. 1988 Dec;95(12):1639-48. doi: 10.1016/s0161-6420(88)32963-5.

DOI:10.1016/s0161-6420(88)32963-5

PMID:3068602

Abstract

Endolaser photocoagulation of the ciliary body was used to treat 42 eyes with severe glaucoma that could not be managed successfully by medical therapy and conventional glaucoma surgery. Follow-up ranged from 6 to 36 months (mean, 13 months). The preoperative intraocular pressure (IOP) ranged from 13 to 76 mmHg (mean, 37 mmHg). The postoperative IOP ranged from 1 to 44 mmHg (mean, 17 mmHg), representing an absolute decrease of 20 mmHg, and a mean decrease of 48%. After one or two (7 eyes) treatment sessions, 11 eyes (26%) had an IOP less than 21 mmHg without medications; 21 eyes (50%) had an IOP less than 21 mmHg with medications; 5 eyes (12%) had an IOP of 21 to 25 mmHg with or without medications; and 5 eyes (12%) had an IOP greater than 25 mmHg. Postoperatively, the number of antiglaucoma medications required was reduced from a mean of 2.8 +/- 0.13 to a mean of 1.4 +/- 0.19. Twenty-three (72%) of 32 patients were able to discontinue carbonic anhydrase inhibitors.

摘要

采用睫状体激光光凝术治疗42例药物治疗和传统青光眼手术无法成功控制的重度青光眼患者。随访时间为6至36个月（平均13个月）。术前眼压范围为13至76 mmHg（平均37 mmHg）。术后眼压范围为1至44 mmHg（平均17 mmHg），绝对降低20 mmHg，平均降低48%。经过一或两个疗程（7只眼）的治疗后，11只眼（26%）在未使用药物的情况下眼压低于21 mmHg；21只眼（50%）在使用药物的情况下眼压低于21 mmHg；5只眼（12%）无论是否使用药物眼压在21至25 mmHg之间；5只眼（12%）眼压高于25 mmHg。术后，所需抗青光眼药物的数量从平均2.8±0.13减少到平均1.4±0.19。32例患者中有23例（72%）能够停用碳酸酐酶抑制剂。