Velin P, DuPont D
Centre médical infantile, Hôpital Lenval pour Enfants, Nice, France.
Pediatrie. 1988;43(9):753-6.
The authors report a case of acute severe hypercalcemia (5.20 mmol/l) in a 9-month-old boy. Vitamin D poisoning is confirmed by high serum level of 25 OHD (287 mcg/l; N = 10-60) while the source of intoxication is unknown. Individual idiopathic vitamin D hypersensitivity is eliminated because of a negative diagnosis test. Management with prednisone, high intravenous fluid saline intake, furosemide and calcitonin results in a favourable outcome. Vitamin D intoxication has always to be evoked when acute severe hypercalcemia occurs in infants.
作者报告了一名9个月大男孩发生急性严重高钙血症(5.20毫摩尔/升)的病例。血清25羟维生素D水平升高(287微克/升;正常范围为10 - 60)证实了维生素D中毒,但中毒来源不明。由于诊断试验为阴性,排除了个体特发性维生素D超敏反应。使用泼尼松、大量静脉输注生理盐水、呋塞米和降钙素进行治疗,结果良好。婴儿发生急性严重高钙血症时,始终要考虑维生素D中毒的可能。