Cody Meissner H
Tufts University School of Medicine, Boston, MA, 02111, USA.
Isr J Health Policy Res. 2019 Jan 28;8(1):15. doi: 10.1186/s13584-019-0288-6.
An analysis of benefit and cost is critical for independent advisory groups that provide evidence-based recommendations. In many countries, the role of RSV immunoprophylaxis for infants at increased risk of hospitalization is controversial because of limited benefit and high cost. The report by Ginsberg and co-workers provides evidence, that in Israel, despite the potential benefit of palivizumab prophylaxis in reducing a small number of RSV hospitalizations but no evidence of long-term benefit, the cost is difficult to justify. Ideally, a safe and effective RSV vaccine or more effective and less expensive monoclonal antibody soon will become available.
对于提供循证建议的独立咨询小组而言,效益和成本分析至关重要。在许多国家,呼吸道合胞病毒(RSV)免疫预防对住院风险增加的婴儿的作用存在争议,原因是效益有限且成本高昂。金斯伯格及其同事的报告提供了证据,即在以色列,尽管帕利珠单抗预防在减少少数RSV住院方面有潜在益处,但没有长期益处的证据,其成本难以说得过去。理想情况下,一种安全有效的RSV疫苗或更有效且更便宜的单克隆抗体很快就会问世。