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心上型部分肺静脉异位连接患者行双补丁术和 Warden 技术的结果。

Outcomes of Double-patch and Warden Techniques in Patients With Supracardiac Partial Anomalous Pulmonary Venous Connection.

机构信息

Congenital Heart Surgery Department, E. Meshalkin National Medical Research Center, Novosibirsk, Russian Federation.

Congenital Heart Surgery Department, E. Meshalkin National Medical Research Center, Novosibirsk, Russian Federation.

出版信息

Heart Lung Circ. 2020 Jan;29(1):156-161. doi: 10.1016/j.hlc.2018.11.020. Epub 2018 Dec 14.

DOI:10.1016/j.hlc.2018.11.020
PMID:30686643
Abstract

AIM

This study compared outcomes following the double-patch and Warden procedures for correcting partial anomalous connection of the right pulmonary veins to the superior vena cava.

METHODS

Eighty (80) patients, aged <18years old, and with partial anomalous connection of the right pulmonary veins to the superior vena cava were randomly assigned into double-patch method (n=40) and Warden procedure (n=40) groups. The median follow-up was 22.5 (range, 12-39) months. The primary endpoint was sinus node dysfunction at the mid-term follow-up period.

RESULTS

No early or late mortality occurred. In the early postoperative period, sinus node dysfunction was observed in 27.5% and 5% of cases after double-patch correction and the Warden procedure, respectively (risk ratio, 5.50; 95% confidence interval, 1.30-23.25; p=0.01). At follow-up, sinus node dysfunction persisted in two (5%) patients after double-patch correction. All patients had normal sinus rhythm after the Warden procedure. No early or late pacemaker implantation occurred in either group. No patients had significant pulmonary veins or superior vena cava stenosis.

CONCLUSIONS

The double-patch technique and Warden procedure both showed excellent early and mid-term results with no mortality and minimal morbidity. The Warden procedure was associated with less sinus node dysfunction in the early postoperative period than the double-patch technique. There was no significant between-group difference in sinus node dysfunction at the mid-term follow-up.

摘要

目的

本研究比较了双补丁法和 Warden 术式治疗部分性肺静脉异常连接至上腔静脉的疗效。

方法

80 例年龄<18 岁、部分性肺静脉异常连接至上腔静脉的患者,随机分为双补丁法(n=40)和 Warden 术式(n=40)组。中位随访时间为 22.5(12-39)个月。主要终点是中期随访时的窦房结功能障碍。

结果

无早期或晚期死亡。在术后早期,双补丁矫正组和 Warden 术式组分别有 27.5%和 5%的患者出现窦房结功能障碍(风险比,5.50;95%置信区间,1.30-23.25;p=0.01)。随访时,双补丁矫正组有 2 例(5%)患者持续存在窦房结功能障碍。所有患者行 Warden 术式后均恢复窦性心律。两组均无早期或晚期起搏器植入。无患者发生明显的肺静脉或上腔静脉狭窄。

结论

双补丁技术和 Warden 术式均具有良好的早期和中期效果,无死亡病例,并发症少。与双补丁技术相比,Warden 术式在术后早期窦房结功能障碍发生率较低。中期随访时,两组间窦房结功能障碍无显著差异。

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