Grieshaber Philippe, Jaschinski Christoph, Farag Mina, Fonseca-Escalante Elizabeth, Gorenflo Matthias, Karck Matthias, Loukanov Tsvetomir
Division of Congenital Cardiac Surgery, Department of Cardiac Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Department of Pediatric Cardiology and Congenital Heart Disease, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Rev Cardiovasc Med. 2024 Sep 29;25(10):350. doi: 10.31083/j.rcm2510350. eCollection 2024 Oct.
Atrial septal defects (ASDs) are among the most prevalent congenital cardiac malformations. Closure of the defect and repair of associated cardiac malformations are typically indicated if an ASD is hemodynamically significant or symptomatic. This narrative review aims to summarize key aspects of surgical ASD closures. A non-systematic literature review was conducted to cover surgically relevant aspects of (developmental) anatomy, morphology, and treatment. ASDs result from diverse developmental alterations, leading to subtype-specific associated cardiac malformations, meaning surgical therapy varies accordingly. Presently, surgical repair yields excellent outcomes for all ASD subtypes, with minimally invasive approaches, especially in adults, increasingly employed for ASD closure. Surgical ASD repair is safe with excellent results. However, familiarity with ASD subtypes and typically associated lesions is crucial for optimal patient management.
房间隔缺损(ASD)是最常见的先天性心脏畸形之一。如果ASD具有血流动力学意义或有症状,通常需要闭合缺损并修复相关的心脏畸形。本叙述性综述旨在总结房间隔缺损手术闭合的关键要点。进行了一项非系统性文献综述,以涵盖(发育)解剖学、形态学和治疗等与手术相关的方面。ASD由多种发育改变引起,导致特定亚型的相关心脏畸形,这意味着手术治疗也相应不同。目前,手术修复对所有ASD亚型都能产生良好效果,微创方法,尤其是在成人中,越来越多地用于ASD闭合。房间隔缺损手术修复安全且效果良好。然而,熟悉ASD亚型和通常相关的病变对于优化患者管理至关重要。