van der Heijde D M, van Riel P L, van Rijswijk M H, van de Putte L B
Department of Rheumatology, University Hospital Nijmegen, The Netherlands.
Semin Arthritis Rheum. 1988 May;17(4):284-92. doi: 10.1016/0049-0172(88)90013-3.
The literature on prognostic features on the final outcome in RA is reviewed. It is generally agreed that female sex and a positive RF are variables indicating a poor prognosis. Longstanding increased ESR and CRP values, decreased Hb, or the appearance of subcutaneous nodules are indicators of a less favorable clinical course. No conclusions can be drawn regarding other factors due to the incomplete and heterogeneous study designs.
本文综述了关于类风湿关节炎（RA）最终结局的预后特征的文献。一般认为，女性和类风湿因子（RF）阳性是提示预后不良的变量。血沉（ESR）和C反应蛋白（CRP）长期升高、血红蛋白（Hb）降低或出现皮下结节是临床病程不太有利的指标。由于研究设计不完整且存在异质性，无法就其他因素得出结论。
