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获得性脑损伤后的下消化道功能障碍:康复过程中的一项挑战。

Lower Bowel Dysfunction Following Acquired Brain Injury: A Challenge During Rehabilitation.

作者信息

Aadal Lena, Mortensen Jesper, Kellenberger Simone, Nielsen Jørgen Feldbæk

机构信息

Lena Aadal, PhD, is Head of Clinical Nursing Research, Hammel Neurorehabilitation and Research Centre, Denmark. Jesper Mortensen, PhD, Hammel Neurorehabilitation and Research Centre, Denmark. Simone Kellenberger, RN, is Education and Development Nurse, Hammel Neurorehabilitation and Research Centre, Denmark. Jørgen Feldbæk Nielsen, MD, DMSc, is Professor, Hammel Neurore habilitation and Research Centre, Denmark.

出版信息

Gastroenterol Nurs. 2019 Jan/Feb;42(1):12-19. doi: 10.1097/SGA.0000000000000352.

Abstract

The aim of this prospective, descriptive cohort study is to describe the prevalence of lower bowel dysfunction, possible relationship to diagnosis and severity, use of laxatives, and defecation patterns in patients with acquired brain injury during inpatient rehabilitation. Enrollment consisted of all patients admitted to an inpatient rehabilitation hospital (n = 98) within a 3-month period and assessments of fecal incontinence and fecal constipation at admission were performed. Documentation of used laxatives, number of defecations, and the macroscopic form during 4 weeks was conducted. Analysis of variance and Kruskal-Wallis analyses were conducted using the statistical software package STATA v 12/IC. At admission 75% of the patients suffered from lower bowel dysfunction, which was related to the severity of injury and age but not major diagnosis or gender. Of these, 68% suffered from fecal incontinence and 32% from fecal constipation. Ninety percent of the patients received laxatives during the initial 28 days. After 28 days, 20% continued to receive laxative treatment. There was no difference between weekly defecations in patients who had functional constipation and patients who had no bowel dysfunction. There was a strong relationship between bowel dysfunction status and prescribed laxative treatment. These findings indicate that lower gastrointestinal dysfunction is a long-lasting, profound complication following an acquired brain injury.

摘要

这项前瞻性描述性队列研究的目的是描述获得性脑损伤患者在住院康复期间下消化道功能障碍的患病率、与诊断及严重程度的可能关系、泻药的使用情况及排便模式。研究对象包括在3个月内入住一家住院康复医院的所有患者(n = 98),并在入院时对大便失禁和便秘情况进行了评估。记录了4周内使用泻药的情况、排便次数及大便的宏观形态。使用统计软件包STATA v 12/IC进行方差分析和Kruskal-Wallis分析。入院时,75%的患者存在下消化道功能障碍,这与损伤严重程度和年龄有关,但与主要诊断或性别无关。其中,68%的患者有大便失禁,32%的患者有便秘。90%的患者在最初28天内接受了泻药治疗。28天后,20%的患者继续接受泻药治疗。功能性便秘患者与无肠道功能障碍患者的每周排便次数无差异。肠道功能障碍状态与规定的泻药治疗之间存在密切关系。这些发现表明,下消化道功能障碍是获得性脑损伤后一种长期、严重的并发症。

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