Department of Pharmacy Practice, University of Rhode Island, Kingston, USA.
Research Department, Veterans Administration Medical Center, Providence, USA.
J Telemed Telecare. 2020 Jun;26(5):294-302. doi: 10.1177/1357633X18822575. Epub 2019 Jan 28.
The aim of this study was to determine whether a pharmacist-led telehealth disease management program is superior to usual care of nurse-led telehealth in improving diabetes medication adherence, haemoglobin A1C (A1C), and depression scores in patients with concomitant diabetes and depression.
Patients with diabetes and depression were randomized to pharmacist-led or nurse-led telehealth. Veterans with type 1 or type 2 diabetes, an A1C ≥ 7.5%, diagnosis of depression, and access to a landline phone were invited to participate. Patients were randomized to usual care of nurse-led telehealth or pharmacist-led telehealth. Patients were shown how to use the telehealth equipment by the nurse or pharmacist. In the pharmacist-led group, the patients received an in-depth medication review in addition to the instruction on the telehealth equipment.
After six months, the pharmacist-led telehealth arm showed significant improvements for cardiovascular medication adherence (14.0; 95% confidence interval (CI) 0.4 to 27.6), antidepressant medication adherence (26.0; 95% CI 0.9 to 51.2), and overall medication adherence combined (13.9; 95% CI 6.6 to 21.2) from baseline to six-month follow-up. There was a significant difference in A1C between each group at the six-month follow-up in the nurse-led telehealth group (6.9 ± 0.9) as compared to the pharmacist-led telehealth group (8.8 ± 2.0). There was no significance in the change in patient health questionnaire-9 (PHQ-9) and Center for Epidemiologic Studies Depression Scale (CES-D) from baseline to follow-up in both groups.
Pharmacist-led telehealth was efficacious in improving medication adherence for cardiovascular, antidepressants, and overall medications over a six-month period as compared to nurse-led telehealth. There was no significant improvement in overall depression scores.
本研究旨在确定药师主导的远程医疗疾病管理计划是否优于常规护理的护士主导的远程医疗,以改善同时患有糖尿病和抑郁症患者的糖尿病药物依从性、糖化血红蛋白(A1C)和抑郁评分。
将患有糖尿病和抑郁症的患者随机分为药师主导或护士主导的远程医疗组。邀请患有 1 型或 2 型糖尿病、A1C≥7.5%、抑郁症诊断且可使用固定电话的退伍军人参加。患者随机分配到常规护理的护士主导远程医疗或药师主导远程医疗。护士或药师向患者展示如何使用远程医疗设备。在药师主导的组中,除了远程医疗设备的指导外,患者还接受了深入的药物审查。
六个月后,与基线相比,药师主导的远程医疗组在心血管药物依从性(14.0;95%置信区间(CI)0.4 至 27.6)、抗抑郁药依从性(26.0;95%CI 0.9 至 51.2)和整体药物依从性(13.9;95%CI 6.6 至 21.2)方面均有显著改善。在护士主导的远程医疗组中,A1C 在六个月的随访时与药师主导的远程医疗组(6.9±0.9)相比有显著差异(8.8±2.0)。两组患者在健康问卷-9(PHQ-9)和流行病学研究抑郁量表(CES-D)方面,从基线到随访均无显著变化。
与护士主导的远程医疗相比,药师主导的远程医疗在六个月内可有效提高心血管、抗抑郁药和整体药物的药物依从性。总体抑郁评分没有显著改善。