脊柱介入-可注射生物材料的最新进展

Spine Intervention-An Update on Injectable Biomaterials.

机构信息

Department of Bioengineering, University of California at Los Angeles, Los Angeles, California, USA; Division of Plastic Surgery, Department of Surgery, Oulu University, Oulu, Finland; School of Technology and Innovations, University of Vaasa, Vaasa, Finland.

Interventional Musculoskeletal Radiology, Clinical Radiology of Oklahoma, Edmond, Oklahoma, USA.

出版信息

Can Assoc Radiol J. 2019 Feb;70(1):37-43. doi: 10.1016/j.carj.2018.11.003.

DOI:10.1016/j.carj.2018.11.003

PMID:30691561

Abstract

Back pain is the second most common reason for primary-care physician visits after the common cold. New understanding of the spine pathophysiology and biomechanics led to the development of novel injectable biomaterials to treat those pain generators. Although not all biomaterials are currently ready for common use, there is significant interest by the medical community to invest time, resources, and energy to optimize these injectables. This review introduces basic concepts and advancements in the field of bioinjectables tailored for the vertebral body. Also, we highlight advances in injectable biomaterials which were presented at the Groupe de Recherche Interdisciplinaire sur les Biomatériaux Ostéoarticulaires Injectables (GRIBOI) (Interdisciplinary Research Society for Injectable Osteoarticular Biomaterials) meeting in March 2018 in Los Angeles, CA. Indeed, multidisciplinary translational research and international meetings such as GRIBOI bring together scientists and clinicians with different backgrounds/expertise to discuss injectable biomaterials innovations tailored for the interventional pain management field.

摘要

背痛是初级保健医生就诊的第二大常见原因，仅次于普通感冒。对脊柱病理生理学和生物力学的新认识促使开发了新型可注射生物材料来治疗这些疼痛源。尽管并非所有生物材料都已准备好普遍使用，但医学界有很大的兴趣投入时间、资源和精力来优化这些可注射物。本综述介绍了为椎体量身定制的生物可注射物领域的基本概念和进展。此外，我们还强调了在 2018 年 3 月于加利福尼亚州洛杉矶举行的 Groupe de Recherche Interdisciplinaire sur les Biomatériaux Ostéoarticulaires Injectables (GRIBOI)（注射式骨关节生物材料跨学科研究学会）会议上展示的可注射生物材料方面的进展。事实上，多学科转化研究和国际会议，如 GRIBOI，汇集了具有不同背景/专业知识的科学家和临床医生，共同讨论针对介入性疼痛管理领域的定制可注射生物材料创新。