Motegi Daisuke, Nagahashi Masayuki, Tsuchida Junko, Moro Kazuki, Niwano Toshiyuki, Yamaura Kumiko, Toshikawa Chie, Hasegawa Miki, Ikarashi Mayuko, Nakajima Masato, Koyama Yu, Kobayashi Takashi, Sakata Jun, Kameyama Hitoshi, Wakai Toshifumi
Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences.
Gan To Kagaku Ryoho. 2018 Dec;45(13):1854-1856.
A 33-year-old woman underwent resection of a right breast mass, which was diagnosed as a fibroadenoma 15 years ago. Ten years later, a right breast mass appeared again, and it was diagnosed as a fibroadenoma based on core needle biopsy. After observation for a while, the mass increased in size, and she underwent resection of the tumor, which was diagnosed as a borderline-malignant phyllodes tumor. A mass appeared again in the right breast and rapidly expanded. A malignant phyllodes tumor was suspected, and right mastectomy was performed. The pathological diagnosis revealed a benign phyllodes tumor. Four years ago, a left breast mass was also detected. Because the mass was suspected to be a fibroadenoma, it has been observed for a few years. The mass has increased in size since 1 year ago, and another mass emerged 2 months ago. Core needle biopsy of the 2 masses revealed that both were phyllodes tumors. She underwent left mastectomy, and the pathological examination revealed that both masses were benign phyllodes tumors. We report this rare case of metachronal phyllodes tumors that presented bilaterally.
一名33岁女性15年前接受了右乳肿块切除术,当时诊断为纤维腺瘤。10年后,右乳再次出现肿块,经粗针活检诊断为纤维腺瘤。观察一段时间后,肿块增大,她接受了肿瘤切除术,术后诊断为交界性叶状肿瘤。右乳再次出现肿块并迅速增大,怀疑为恶性叶状肿瘤,遂行右乳切除术。病理诊断为良性叶状肿瘤。4年前,左乳也发现了肿块。由于怀疑该肿块为纤维腺瘤,已观察数年。自1年前起肿块增大,2个月前又出现了另一个肿块。对这两个肿块进行粗针活检显示均为叶状肿瘤。她接受了左乳切除术,病理检查显示两个肿块均为良性叶状肿瘤。我们报告了这例罕见的双侧异时性叶状肿瘤病例。