采用治疗性血浆置换成功治疗严重高甘油三酯血症性胰腺炎：来自印度的报告
Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India.
作者信息
Mehta Swati Pabbi, Tiwari Aseem Kumar, Puri Rajesh, Arora Dinesh, Aggarwal Geet, Ratan Ankita
机构信息
Department of Transfusion Medicine, Medanta - The Medicity, Gurgaon, Haryana, India.
Department of Gastroenterology and Hepatology, Medanta - The Medicity, Gurgaon, Haryana, India.
出版信息
Asian J Transfus Sci. 2018 Jul-Dec;12(2):154-156. doi: 10.4103/ajts.AJTS_86_17.
Abstract
Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. He was treated with TPE along with intravenous insulin, statins, and fibrates. TPE resulted in immediate relief of symptoms as well as a marked improvement in laboratory values, with 74.5% reduction in triglycerides after a single session. TPE can be successfully utilized as an adjunct in HTG-induced pancreatitis.
摘要
高甘油三酯血症（HTG）是继胆结石和酒精之后急性胰腺炎的第三大重要危险因素。治疗性血浆置换（TPE）被认为是治疗HTG诱发胰腺炎的一种可能方法，尤其是在重症和难治性病例中。在此，我们报告一例严重HTG诱发胰腺炎患者的临床经验。他接受了TPE治疗，并同时使用了静脉胰岛素、他汀类药物和贝特类药物。TPE使症状立即得到缓解，实验室检查值也显著改善，单次治疗后甘油三酯降低了74.5%。TPE可成功用作HTG诱发胰腺炎的辅助治疗方法。
相似文献
1
Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India.采用治疗性血浆置换成功治疗严重高甘油三酯血症性胰腺炎：来自印度的报告
Asian J Transfus Sci. 2018 Jul-Dec;12(2):154-156. doi: 10.4103/ajts.AJTS_86_17.
2
Therapeutic plasma exchange for hypertriglyceridemia induced acut pancreatitis: the 33 cases experience from a tertiary reference center in Turkey.治疗性血浆置换治疗高甘油三酯血症性急性胰腺炎：来自土耳其一家三级转诊中心的33例经验
Turk J Gastroenterol. 2018 Nov;29(6):676-683. doi: 10.5152/tjg.2018.17627.
3
Effect of TPE vs medical management on patient outcomes in the setting of hypertriglyceridemia-induced acute pancreatitis with severely elevated triglycerides.在高甘油三酯血症诱导的急性胰腺炎且甘油三酯严重升高的情况下，治疗性血浆置换（TPE）与药物治疗对患者预后的影响。
J Clin Apher. 2021 Oct;36(5):719-726. doi: 10.1002/jca.21922. Epub 2021 Jul 6.
4
Effect of Plasma Exchange Treatment in Patients with Hypertriglyceridemia-Induced Acute Pancreatitis.血浆置换治疗对高甘油三酯血症性急性胰腺炎患者的影响。
Medicina (Kaunas). 2023 Apr 29;59(5):864. doi: 10.3390/medicina59050864.
5
Treatment of severe hypertriglyceridemia through therapeutic plasma exchange in patients with acute pancreatitis or at risk of developing it.通过治疗性血浆置换治疗急性胰腺炎患者或有发生急性胰腺炎风险患者的严重高甘油三酯血症。
Gastroenterol Hepatol. 2025 Jan;48(1):502229. doi: 10.1016/j.gastrohep.2024.502229. Epub 2024 Jul 9.
6
Use of the APACHE II score to assess impact of therapeutic plasma exchange for critically ill patients with hypertriglyceride-induced pancreatitis.使用急性生理学及慢性健康状况评分系统II（APACHE II）评估治疗性血浆置换对重症高甘油三酯血症性胰腺炎患者的影响。
Transfus Apher Sci. 2017 Apr;56(2):123-126. doi: 10.1016/j.transci.2016.10.005. Epub 2016 Oct 17.
7
Comparative efficacy of therapeutic plasma exchange and insulin in hypertriglyceridemia-induced acute pancreatitis.治疗性血浆置换与胰岛素治疗高甘油三酯血症性急性胰腺炎的疗效比较
Indian J Gastroenterol. 2024 Aug 28. doi: 10.1007/s12664-024-01669-0.
8
Emergent therapy with therapeutic plasma exchange in acute recurrent pancreatitis due to severe hypertriglyceridemia.严重高甘油三酯血症所致急性复发性胰腺炎的治疗性血浆置换紧急治疗
Transfus Apher Sci. 2010 Dec;43(3):285-289. doi: 10.1016/j.transci.2010.09.009.
9
Predictability and efficacy of therapeutic plasma exchange for hypertriglyceridemia induced acute pancreatitis.治疗性血浆置换对高甘油三酯血症性急性胰腺炎的可预测性及疗效
Transfus Apher Sci. 2020 Apr;59(2):102699. doi: 10.1016/j.transci.2019.102699. Epub 2019 Dec 24.
10
Therapeutic plasma exchange for hypertriglyceridemia induced pancreatitis: A rapid and practical approach.治疗性血浆置换治疗高甘油三酯血症性胰腺炎：一种快速实用的方法。
Transfus Apher Sci. 2016 Feb;54(1):99-102. doi: 10.1016/j.transci.2016.02.001. Epub 2016 Feb 20.
引用本文的文献
1
Plasmapheresis for Hypertriglyceridemia-induced Acute Pancreatitis: A Systematic Review and Meta-summary of Case Reports.血浆置换治疗高甘油三酯血症性急性胰腺炎：病例报告的系统评价和Meta总结
Indian J Crit Care Med. 2025 Jul;29(7):604-611. doi: 10.5005/jp-journals-10071-25010. Epub 2025 Jul 7.
2
Timely Application of Plasma Exchange to Correct Acute Pancreatitis Related to Serum Triglyceride Levels: A Report of 6 Cases and a Literature Review.及时应用血浆置换纠正与血清甘油三酯水平相关的急性胰腺炎：6例报告及文献综述
Am J Case Rep. 2024 Dec 21;25:e944763. doi: 10.12659/AJCR.944763.
本文引用的文献
1
Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Seventh Special Issue.《临床实践中治疗性血液成分单采的使用指南——美国血液成分单采协会写作委员会基于证据的方法：第七期特刊》
J Clin Apher. 2016 Jun;31(3):149-62. doi: 10.1002/jca.21470.
2
Factors affecting outcome in acute hypertriglyceridemic pancreatitis treated with plasma exchange: an observational cohort study.血浆置换治疗急性高甘油三酯血症性胰腺炎的预后影响因素：一项观察性队列研究
PLoS One. 2014 Jul 21;9(7):e102748. doi: 10.1371/journal.pone.0102748. eCollection 2014.
3
Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.评估与治疗高甘油三酯血症：内分泌学会临床实践指南。
J Clin Endocrinol Metab. 2012 Sep;97(9):2969-89. doi: 10.1210/jc.2011-3213.
4
Treatment options for severe hypertriglyceridemia (SHTG): the role of apheresis.重度高甘油三酯血症（SHTG）的治疗选择：血液成分分离术的作用
Clin Res Cardiol Suppl. 2012 Jun;7(Suppl 1):31-5. doi: 10.1007/s11789-012-0042-x.
5
Plasmapheresis in the treatment of hypertriglyceridemia-induced pancreatitis: A community hospital's experience.血浆置换治疗高甘油三酯血症性胰腺炎：一家社区医院的经验
J Clin Apher. 2010;25(4):229-34. doi: 10.1002/jca.20232.
6
Therapeutic plasma exchange in patients with severe hypertriglyceridemia: a multicenter study.严重高甘油三酯血症患者的治疗性血浆置换：一项多中心研究。
Artif Organs. 2009 Dec;33(12):1096-102. doi: 10.1111/j.1525-1594.2009.00810.x.
7
Predictors of complications in therapeutic plasma exchange.治疗性血浆置换并发症的预测因素。
J Clin Apher. 2009;24(6):225-31. doi: 10.1002/jca.20217.
8
Management of acute severe hyperlipidemic pancreatitis.急性重症高脂血症性胰腺炎的管理
Digestion. 2006;73(4):259-64. doi: 10.1159/000095425. Epub 2006 Aug 28.
9
Plasmapheresis for hyperlipidemic pancreatitis.用于高脂血症性胰腺炎的血浆置换术。
J Clin Apher. 2003;18(4):181-5. doi: 10.1002/jca.10063.
10
Issues in hyperlipidemic pancreatitis.高脂血症性胰腺炎相关问题
J Clin Gastroenterol. 2003 Jan;36(1):54-62. doi: 10.1097/00004836-200301000-00016.
Zotero 插件