喉咽反流中分泌性中耳炎的患病率比值
Prevalence Ratio of Otitis Media with Effusion in Laryngopharyngeal Reflux.
作者信息
Karyanta Mahastini, Satrowiyoto Siswanto, Wulandari Dian Paramita
机构信息
Faculty of Medicine, Public Health and Nursing Gadjah Mada University/Sardjito General Hospital, Yogyakarta, Indonesia.
出版信息
Int J Otolaryngol. 2019 Jan 1;2019:7460891. doi: 10.1155/2019/7460891. eCollection 2019.
BACKGROUND
Otitis media with effusion (OME) in adults is less prevalent than in the pediatric population but still causes considerable morbidity. It has been suggested that laryngopharyngeal reflux (LPR) may have a role in the aetiology of adult OME. Reflux advances to the laryngopharynx and, subsequently, to other regions of the head and neck such as oral cavity, nasopharynx, nasal cavity, paranasal sinuses, and even middle ear with clinical manifestations being asthma, sinusitis, and otitis media.
OBJECTIVE
To determine the prevalence ratio of otitis media with effusion in laryngopharyngeal reflux.
METHODS
Observational analytic with cross sectional design.
RESULT
9 of 28 subjects experienced OME in LPR group, and 2 of 28 subjects in non-LPR group. Statistically there was significant difference between the two groups with p-value 0.02 and with 95% confidence interval range of 1.066-18.990.
CONCLUSION
The prevalence ratio of otitis media with effusion in laryngopharyngeal reflux group is 4.5 times that in non-laryngopharyngeal reflux group.
背景
成人分泌性中耳炎（OME）的发病率低于儿童群体，但仍会导致相当高的发病率。有人认为，喉咽反流（LPR）可能在成人OME的病因中起作用。反流会蔓延至喉咽部，随后蔓延至头颈部的其他区域，如口腔、鼻咽、鼻腔、鼻窦，甚至中耳，临床表现为哮喘、鼻窦炎和中耳炎。
目的
确定喉咽反流患者中分泌性中耳炎的患病率。
方法
采用横断面设计的观察性分析。
结果
LPR组28名受试者中有9人患OME，非LPR组28名受试者中有2人患OME。两组之间在统计学上有显著差异，p值为0.02，95%置信区间范围为1.066 - 18.990。
结论
喉咽反流组分泌性中耳炎的患病率是非喉咽反流组的4.5倍。
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