• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Prevalence Ratio of Otitis Media with Effusion in Laryngopharyngeal Reflux.喉咽反流中分泌性中耳炎的患病率比值
Int J Otolaryngol. 2019 Jan 1;2019:7460891. doi: 10.1155/2019/7460891. eCollection 2019.
2
Clinical evaluation of pepsin for laryngopharyngeal reflux in children with otitis media with effusion.胃蛋白酶在分泌性中耳炎患儿喉咽反流中的临床评估
Int J Pediatr Otorhinolaryngol. 2013 Oct;77(10):1765-70. doi: 10.1016/j.ijporl.2013.08.014. Epub 2013 Aug 22.
3
Role of pepsin and pepsinogen: linking laryngopharyngeal reflux with otitis media with effusion in children.胃蛋白酶和胃蛋白酶原的作用：儿童喉咽反流与分泌性中耳炎的关联
Laryngoscope. 2014 Jul;124(7):E294-300. doi: 10.1002/lary.24538. Epub 2014 Jan 15.
4
Linking laryngopharyngeal reflux to otitis media with effusion: pepsinogen study of adenoid tissue and middle ear fluid.将喉咽反流与分泌性中耳炎相联系：腺样体组织和中耳积液的胃蛋白酶原研究
J Otolaryngol Head Neck Surg. 2008 Aug;37(4):565-71.
5
Factors affecting the occurrence of otitis media with effusion in preschool and elementary school children: a comparative cross-sectional study.影响学龄前和小学生分泌性中耳炎发生的因素：一项比较性横断面研究。
BMJ Open. 2022 Sep 28;12(9):e065291. doi: 10.1136/bmjopen-2022-065291.
6
Prevalence of laryngopharyngeal reflux symptoms: comparison between health checkup examinees and patients with otitis media.咽喉反流症状的流行率：健康体检者与中耳炎患者的比较。
Otolaryngol Head Neck Surg. 2012 Apr;146(4):562-6. doi: 10.1177/0194599811434049. Epub 2012 Jan 27.
7
Laryngopharyngeal Reflux in Children with Chronic Otitis Media with Effusion.伴有积液的慢性中耳炎患儿的喉咽反流
J Neurogastroenterol Motil. 2016 Jul 30;22(3):452-8. doi: 10.5056/jnm16013.
8
[Correlation between laryngopharyngeal reflux and otitis media with effusion in adults patients].[成年患者喉咽反流与中耳积液的相关性]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Aug 5;32(15):1167-1170. doi: 10.13201/j.issn.1001-1781.2018.15.010.
9
Association between otitis media and gastroesophageal reflux: a systematic review.中耳炎与胃食管反流的关系：系统评价。
Otolaryngol Head Neck Surg. 2012 Mar;146(3):345-52. doi: 10.1177/0194599811430809. Epub 2011 Dec 9.
10
Role of Laryngopharyngeal Reflux in the Pathogenesis of Otitis Media with Effusion.喉咽反流在分泌性中耳炎发病机制中的作用。
J Int Adv Otol. 2015 Apr;11(1):66-71. doi: 10.5152/iao.2015.642.

引用本文的文献

1
Factors affecting the occurrence of otitis media with effusion in preschool and elementary school children: a comparative cross-sectional study.影响学龄前和小学生分泌性中耳炎发生的因素：一项比较性横断面研究。
BMJ Open. 2022 Sep 28;12(9):e065291. doi: 10.1136/bmjopen-2022-065291.
2
Ear, nose and throat (ENT) manifestations and complications of reflux.反流的耳、鼻、喉（ENT）表现及并发症
Frontline Gastroenterol. 2022 Jun 7;13(e1):e57-e64. doi: 10.1136/flgastro-2022-102184. eCollection 2022.
3
Patients Requiring Gastrostomy Tube Insertion After Total Laryngectomy Have a Higher Incidence of Otitis Media.全喉切除术后需要插入胃造瘘管的患者中耳炎发病率较高。
J Audiol Otol. 2022 Jan;26(1):31-35. doi: 10.7874/jao.2021.00549. Epub 2021 Dec 30.

本文引用的文献

1
Aetiology and pathology of otitis media with effusion in adult life.成人分泌性中耳炎的病因与病理
J Laryngol Otol. 2016 May;130(5):418-24. doi: 10.1017/S0022215116000943. Epub 2016 Mar 15.
2
Nasopharyngeal acid reflux and Eustachian tube dysfunction in adults.成人鼻咽部酸反流与咽鼓管功能障碍
Ann Otol Rhinol Laryngol. 2014 Jun;123(6):415-9. doi: 10.1177/0003489414526689.
3
Prevalence of laryngopharyngeal reflux symptoms: comparison between health checkup examinees and patients with otitis media.咽喉反流症状的流行率：健康体检者与中耳炎患者的比较。
Otolaryngol Head Neck Surg. 2012 Apr;146(4):562-6. doi: 10.1177/0194599811434049. Epub 2012 Jan 27.
4
Anatomy of reflux: a growing health problem affecting structures of the head and neck.反流的解剖学：一个影响头颈部结构的日益严重的健康问题。
Anat Rec B New Anat. 2006 Nov;289(6):261-70. doi: 10.1002/ar.b.20120.
5
Clinical practice guideline: Otitis media with effusion.临床实践指南：中耳积液
Otolaryngol Head Neck Surg. 2004 May;130(5 Suppl):S95-118. doi: 10.1016/j.otohns.2004.02.002.
6
Laryngopharyngeal reflux: position statement of the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology-Head and Neck Surgery.喉咽反流：美国耳鼻咽喉-头颈外科学会言语、嗓音和吞咽障碍委员会的立场声明
Otolaryngol Head Neck Surg. 2002 Jul;127(1):32-5. doi: 10.1067/mhn.2002.125760.
7
The validity and reliability of the reflux finding score (RFS).反流发现评分（RFS）的有效性和可靠性。
Laryngoscope. 2001 Aug;111(8):1313-7. doi: 10.1097/00005537-200108000-00001.

喉咽反流中分泌性中耳炎的患病率比值

Prevalence Ratio of Otitis Media with Effusion in Laryngopharyngeal Reflux.

作者信息

Karyanta Mahastini, Satrowiyoto Siswanto, Wulandari Dian Paramita

机构信息

Faculty of Medicine, Public Health and Nursing Gadjah Mada University/Sardjito General Hospital, Yogyakarta, Indonesia.

出版信息

Int J Otolaryngol. 2019 Jan 1;2019:7460891. doi: 10.1155/2019/7460891. eCollection 2019.

DOI:10.1155/2019/7460891
PMID:30693036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6332939/
Abstract

BACKGROUND

Otitis media with effusion (OME) in adults is less prevalent than in the pediatric population but still causes considerable morbidity. It has been suggested that laryngopharyngeal reflux (LPR) may have a role in the aetiology of adult OME. Reflux advances to the laryngopharynx and, subsequently, to other regions of the head and neck such as oral cavity, nasopharynx, nasal cavity, paranasal sinuses, and even middle ear with clinical manifestations being asthma, sinusitis, and otitis media.

OBJECTIVE

To determine the prevalence ratio of otitis media with effusion in laryngopharyngeal reflux.

METHODS

Observational analytic with cross sectional design.

RESULT

9 of 28 subjects experienced OME in LPR group, and 2 of 28 subjects in non-LPR group. Statistically there was significant difference between the two groups with p-value 0.02 and with 95% confidence interval range of 1.066-18.990.

CONCLUSION

The prevalence ratio of otitis media with effusion in laryngopharyngeal reflux group is 4.5 times that in non-laryngopharyngeal reflux group.

摘要

背景

成人分泌性中耳炎（OME）的发病率低于儿童群体，但仍会导致相当高的发病率。有人认为，喉咽反流（LPR）可能在成人OME的病因中起作用。反流会蔓延至喉咽部，随后蔓延至头颈部的其他区域，如口腔、鼻咽、鼻腔、鼻窦，甚至中耳，临床表现为哮喘、鼻窦炎和中耳炎。

目的

确定喉咽反流患者中分泌性中耳炎的患病率。

方法

采用横断面设计的观察性分析。

结果

LPR组28名受试者中有9人患OME，非LPR组28名受试者中有2人患OME。两组之间在统计学上有显著差异，p值为0.02，95%置信区间范围为1.066 - 18.990。

结论

喉咽反流组分泌性中耳炎的患病率是非喉咽反流组的4.5倍。