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胶原蛋白衍生去蛋白牛骨在无瓣即刻种植及即刻临时修复中改善软组织和骨组织效果:一项随机临床试验。

Deproteinized bovine bone derived with collagen improves soft and bone tissue outcomes in flapless immediate implant approach and immediate provisionalization: a randomized clinical trial.

机构信息

Dental Research Division, School of Dentistry, Universidade Paulista (UNIP), Av. Dr. Bacelar, 1212, 4º andar, Vila Clementino, São Paulo, SP, 04026-002, Brazil.

出版信息

Clin Oral Investig. 2019 Oct;23(10):3885-3893. doi: 10.1007/s00784-019-02819-x. Epub 2019 Jan 28.

Abstract

OBJECTIVES

This study aimed at evaluating soft and hard tissue dimensions after immediate implant placement and immediate temporization with or without alveolar preservation at the maxillary anterior region.

MATERIALS AND METHODS

Twenty-two patients needing maxillary incisor extraction and with the possibility of immediate implant placement were randomly assigned to the following groups: test (n = 11): immediate implant placement + deproteinized bovine bone derived with collagen inserted into the alveolus or control (n = 11): immediate implant placement without biomaterial. All soft tissue measurements were evaluated at baseline, 3 months, and 6 months after implant therapy. Cone beam tomography was performed at baseline and at 6 months after implant placement to evaluate hard tissue dimension.

RESULTS

The test group presented higher height of soft tissue at mesiobuccal and distobuccal sites at 3 months and 6 months when compared to the control group (p < 0.05). Regarding the bone tissue, the test group showed higher buccolingual ridge dimension at 6 months when compared to the control group (p < 0.05).

CONCLUSIONS

It can be concluded that the use of deproteinized bovine bone derived with collagen together with immediate dental implants results in better soft and bone tissue outcomes than immediate implants alone.

CLINICAL RELEVANCE

The use of deproteinized bovine bone derived with collagen may enhance the results regarding soft and bone tissue in combination with immediate implant and temporization.

摘要

目的

本研究旨在评估在上颌前牙区即刻种植及即刻临时修复时,采用或不采用牙槽骨保存方法对软组织和硬组织的影响。

材料与方法

22 名需要上颌切牙拔除且具备即刻种植条件的患者被随机分为两组:实验组(n=11):即刻种植+脱蛋白牛骨胶原植入牙槽窝;对照组(n=11):即刻种植但不使用生物材料。所有软组织测量均在基线、种植治疗后 3 个月和 6 个月进行评估。在基线和种植治疗后 6 个月时行锥形束 CT 检查以评估硬组织维度。

结果

与对照组相比,实验组在 3 个月和 6 个月时近中颊侧和远中颊侧的软组织高度更高(p<0.05)。在骨组织方面,实验组在 6 个月时颊舌向牙槽嵴宽度更高(p<0.05)。

结论

与单独即刻种植相比,使用脱蛋白牛骨胶原联合即刻种植可获得更好的软组织和骨组织效果。

临床意义

与即刻种植和临时修复联合使用脱蛋白牛骨胶原可能会增强软组织和骨组织的效果。

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