Bender Monika, Romei Vincenzo, Sauseng Paul
Department of Psychology, Ludwig-Maximilians-Universität München, Leopoldstr. 13, 80802, Munich, Germany.
Dipartimento di Psicologia, Università di Bologna, Campus di Cesena, Viale Europa, Cesena, Italy.
Brain Topogr. 2019 May;32(3):477-481. doi: 10.1007/s10548-019-00702-2. Epub 2019 Jan 29.
Recent research suggests alteration of visual working memory capacity by modulation of parietal theta frequency via transcranial alternating current stimulation (tACS). However, it remains to be clarified whether this effect is partly driven by co-stimulation of prefrontal cortex and subcortical structures. It was hypothesized that focal tACS over the parietal lobe without additional prefrontal or subcortical stimulation should lead to similar effects as reported in the literature. Healthy, young participants were tested on a visual working memory paradigm while receiving either focal parietal tACS at 4 Hz, at 7 Hz or sham stimulation. Focal right posterior 4 Hz tACS led to increased working memory capacity strictly for the visual hemifield contralateral to stimulation. Exclusive stimulation of posterior cortex by 4 Hz tACS replicates effects recently reported in literature, confirming that stimulation of the prefrontal cortex or subcortical structures are not a primary driver of these observations.
最近的研究表明，通过经颅交流电刺激（tACS）调节顶叶θ频率可改变视觉工作记忆容量。然而，这种效应是否部分由前额叶皮层和皮层下结构的共同刺激驱动仍有待阐明。据推测，在没有额外前额叶或皮层下刺激的情况下，对顶叶进行局部tACS应会产生与文献报道相似的效果。健康的年轻参与者在视觉工作记忆范式下接受测试，同时接受4赫兹、7赫兹的局部顶叶tACS或伪刺激。右侧顶叶后部4赫兹的局部tACS严格地导致了与刺激对侧视觉半视野相关的工作记忆容量增加。4赫兹tACS对后皮层的单独刺激重复了最近文献中报道的效应，证实前额叶皮层或皮层下结构的刺激不是这些观察结果的主要驱动因素。
