Salzer Jonatan, Zizka Jan, Karlberg Mikael
Institutionen för farmakologi och klinisk neurovetenskap - Sektionen för neurologi Sweden, Sweden Institutionen för farmakologi och klinisk neurovetenskap - Sektionen för neurologi Sweden, Sweden.
Norrlands universitetssjukhus - Bild- och funktionsmedicin, Neuroradiologi Umeå, Sweden Norrlands universitetssjukhus - Bild- och funktionsmedicin, Neuroradiologi Umeå, Sweden.
Lakartidningen. 2019 Jan 24;116:FEP4.
Wernicke encephalopathy is a condition in which thiamine deficiency causes cognitive dysfunction, ataxia and eye motor abnormalities. The condition is potentially reversible if treated with high doses of intravenous thiamine (vitamin B1). The video head impulse test, in which the vestibulo-ocular reflex is tested, can reveal an early specific sign of selective dysfunction in the medial vestibular nuclei by demonstrating selective dysfunction of the horisontal vestibulo-ocular reflex. We present two cases with clinical and neuroradiological findings consistent with Wernicke encephalopathy where such oculomotor findings were detected.
韦尼克脑病是一种因硫胺素缺乏导致认知功能障碍、共济失调和眼球运动异常的病症。若用大剂量静脉注射硫胺素(维生素B1)治疗,该病症可能可逆。视频头脉冲试验用于测试前庭眼反射,通过显示水平前庭眼反射的选择性功能障碍,可揭示内侧前庭核早期特定的选择性功能障碍体征。我们报告两例临床和神经放射学表现符合韦尼克脑病的病例,其中检测到了此类眼球运动表现。