Zuccoli Giulio, Motti Luisa
Radiology Department, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy.
J Neuroimaging. 2008 Apr;18(2):194-7. doi: 10.1111/j.1552-6569.2007.00188.x. Epub 2007 Oct 18.
Wernicke's encephalopathy (WE) is a severe neurological disorder caused by a dietary deficiency of Vitamin B1 and characterized by consciousness changes, ocular abnormalities, and ataxia. Wernicke's encephalopathy is considered a medical emergency and treatment consists of intravenous thiamine administration. Typically in alcoholic and nonalcoholic patients magnetic resonance shows alterations in the mamillary bodies, medial thalami, tectal plate, and periaqueductal regions. We report here on a nonalcoholic atypical case of WE which presented with reversible symmetrical lesions in the cranial nerves nuclei and in the cerebellum alongside the classic neuroradiological findings.
韦尼克脑病(WE)是一种由维生素B1饮食缺乏引起的严重神经障碍,其特征为意识改变、眼部异常和共济失调。韦尼克脑病被视为医疗急症,治疗方法包括静脉注射硫胺素。在酒精性和非酒精性患者中,磁共振成像通常显示乳头体、丘脑内侧、中脑顶盖和导水管周围区域有改变。我们在此报告一例非酒精性韦尼克脑病的非典型病例,该病例除了具有典型的神经放射学表现外,还在颅神经核和小脑中出现了可逆的对称性病变。