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与塑料和橡胶耗材中的抗氧化剂相关的潜在毒理学问题。

Potential toxicological problems associated with antioxidants in plastics and rubber consumables.

作者信息

Scott G

机构信息

Polymer Group, Aston University, Birmingham.

出版信息

Free Radic Res Commun. 1988;5(3):141-7. doi: 10.3109/10715768809066923.

DOI:10.3109/10715768809066923
PMID:3069614
Abstract

Antioxidants and stabilisers are of critical importance in the manufacture and use of polymer artifacts. Most conventional additives are readily leached from plastics or rubbers by foodstuffs or body fluids with consequent danger associated with the potential toxicity in the body. Strategy for the development of biologically "safe" stabilisation systems for polymers are discussed and it is concluded that the attachment of the appropriate reactive functional group to the polymer backbone by "reactive processing" provides the best means of immobilising the functional group to leaching fluids without sacrificing its protective action.

摘要

抗氧化剂和稳定剂在聚合物制品的制造和使用中至关重要。大多数传统添加剂很容易被食品或体液从塑料或橡胶中浸出,从而带来与体内潜在毒性相关的危险。本文讨论了开发聚合物生物“安全”稳定系统的策略,得出的结论是,通过“反应加工”将适当的反应性功能基团连接到聚合物主链上,是将功能基团固定在浸出液中而不牺牲其保护作用的最佳方法。

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Potential toxicological problems associated with antioxidants in plastics and rubber consumables.与塑料和橡胶耗材中的抗氧化剂相关的潜在毒理学问题。
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Studies on the toxicity and skin effects of compounds used in the rubber and plastics industries. I. Accelerators, activators, and antioxidants.橡胶和塑料工业中使用的化合物的毒性和皮肤影响研究。I. 促进剂、活性剂和抗氧化剂。
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The toxicity of rubbers and plastics used in transfusion-giving sets.输血器具中使用的橡胶和塑料的毒性。
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Tell me about free radicals, doctor: a review.医生,请给我讲讲自由基:一篇综述。
J R Soc Med. 1989 Dec;82(12):747-52. doi: 10.1177/014107688908201216.
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Free radicals, reactive oxygen species and human disease: a critical evaluation with special reference to atherosclerosis.自由基、活性氧与人类疾病:特别参照动脉粥样硬化的批判性评估
Br J Exp Pathol. 1989 Dec;70(6):737-57.