Scott G
Polymer Group, Aston University, Birmingham.
Free Radic Res Commun. 1988;5(3):141-7. doi: 10.3109/10715768809066923.
Antioxidants and stabilisers are of critical importance in the manufacture and use of polymer artifacts. Most conventional additives are readily leached from plastics or rubbers by foodstuffs or body fluids with consequent danger associated with the potential toxicity in the body. Strategy for the development of biologically "safe" stabilisation systems for polymers are discussed and it is concluded that the attachment of the appropriate reactive functional group to the polymer backbone by "reactive processing" provides the best means of immobilising the functional group to leaching fluids without sacrificing its protective action.
抗氧化剂和稳定剂在聚合物制品的制造和使用中至关重要。大多数传统添加剂很容易被食品或体液从塑料或橡胶中浸出,从而带来与体内潜在毒性相关的危险。本文讨论了开发聚合物生物“安全”稳定系统的策略,得出的结论是,通过“反应加工”将适当的反应性功能基团连接到聚合物主链上,是将功能基团固定在浸出液中而不牺牲其保护作用的最佳方法。