Pujol R M, Puig L, García-Marques J M, de Moragas J M
Department of Dermatology, Hospital Sant Pau, Barcelona, Spain.
Int J Dermatol. 1988 Dec;27(10):688-9. doi: 10.1111/j.1365-4362.1988.tb01264.x.
A 70-year-old man with hypertrophic osteoartropathy secondary to a squamous cell carcinoma of the lung presented a distinctive pattern of late-onset bilateral palmar keratoderma. A yellowish rugose appearance with accentuation of normal ridges and sulci (pachydermatoglyphy) involving the palms was observed. The differential diagnosis and the clinical relevance of acquired pachydermatoglyphy as a cutaneous marker of internal malignancy are discussed.
