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[醋酸格拉替雷(泰科希)对复发缓解型多发性硬化症患者视网膜神经层神经退行性变过程体征的影响]

[An impact of glatiramer acetate (timexon) on the signs of neurodegeneration process in the neuronal layer of the retina in patients with relapsing-remitting multiple sclerosis].

作者信息

Sazonov D V, Babenko L A, Yarmoschuk A V, Didrikh E M

机构信息

'Siberian District Medical Center of the Federal Medical and Biological Agency' of Russia, Novosibirsk, Russia.

Medical center 'Avicenna' group of companies 'Mother and Child', Novosibirsk, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(12):25-30. doi: 10.17116/jnevro201811812125.

DOI:10.17116/jnevro201811812125
PMID:30698556
Abstract

AIM

To perform a comparative study of the results of optical coherence tomography of the retina in patients with relapsing-remitting multiple sclerosis, treated with glatiramer acetate (timexon).

MATERIAL AND METHODS

The study included 19 patients (16 women and 3 men) with relapsing-remitting multiple sclerosis who were treated with the glatiramer acetate generic drug timexon (BIOCAD, Russia). Dynamic changes in the main parameters of the optical coherence tomography linked with neurodegeneration manifestations in the retina during the year of the study were evaluated.

RESULTS AND CONCLUSION

The efficacy of timexon in the progression of neurodegenerative changes in the retina was shown.

摘要

目的

对接受醋酸格拉替雷(替罗非班)治疗的复发缓解型多发性硬化症患者的视网膜光学相干断层扫描结果进行比较研究。

材料与方法

该研究纳入了19例复发缓解型多发性硬化症患者(16名女性和3名男性),他们接受了醋酸格拉替雷仿制药替罗非班(俄罗斯BIOCAD公司生产)的治疗。评估了在研究的一年中,与视网膜神经变性表现相关的光学相干断层扫描主要参数的动态变化。

结果与结论

显示了替罗非班在视网膜神经退行性变进展方面的疗效。

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[An impact of glatiramer acetate (timexon) on the signs of neurodegeneration process in the neuronal layer of the retina in patients with relapsing-remitting multiple sclerosis].[醋酸格拉替雷(泰科希)对复发缓解型多发性硬化症患者视网膜神经层神经退行性变过程体征的影响]
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(12):25-30. doi: 10.17116/jnevro201811812125.
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[Treatment of multiple sclerosis with glatiramer acetate: a new look].
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Equivalence of Generic Glatiramer Acetate in Multiple Sclerosis: A Randomized Clinical Trial.多发性硬化症中通用型醋酸格拉替雷的等效性:一项随机临床试验。
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Benefit of endermology on indurations and panniculitis/lipoatrophy during relapsing-remitting multiple sclerosis long-term treatment with glatiramer acetate.在醋酸格拉替雷长期治疗复发缓解型多发性硬化症期间,经皮电刺激神经疗法对硬结和脂膜炎/脂肪萎缩的益处。
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QualiCOP: real-world effectiveness, tolerability, and quality of life in patients with relapsing-remitting multiple sclerosis treated with glatiramer acetate, treatment-naïve patients, and previously treated patients.QuliCop 研究:初治和既往治疗的复发缓解型多发性硬化患者接受醋酸格拉替雷治疗的真实世界疗效、耐受性和生活质量。
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