Malleson P, Petty R E, Nadel H, Dimmick J E
Department of Paediatrics, University of British Columbia, Vancouver, Canada.
J Rheumatol. 1988 Nov;15(11):1648-52.
Fatal pneumococcal sepsis due to functional asplenia in a child with systemic lupus erythematosus (SLE) and transient hyposplenism in a 2nd child during an acute flare of SLE are described. Splenic ultrasound examinations and radionuclide spleen scans in 11 other children with SLE were normal. Splenic atrophy and dysfunction is an uncommon but potentially fatal complication of SLE in childhood.
本文描述了一名患有系统性红斑狼疮（SLE）的儿童因功能性无脾导致的致命性肺炎球菌败血症，以及另一名儿童在SLE急性发作期间出现的短暂性脾功能减退。对其他11名SLE患儿进行的脾脏超声检查和放射性核素脾扫描结果均正常。脾脏萎缩和功能障碍是儿童SLE中一种罕见但可能致命的并发症。
