Wilson W A, Perez M C, Marwah R, Foreman J B, McGrath H
Department of Medicine, Louisiana State University Medical Center, New Orleans 70112.
Clin Exp Rheumatol. 1989 May-Jun;7(3):251-5.
The relationship between quantitative splenic uptake of sulfur colloid and immunoglobulin M level in serum was studied in 15 patients with systemic lupus erythematosus (SLE). Splenic function correlated positively with IgM level (r = 0.58, p = 0.02) and inversely with antibody titre to n-DNA (r = -0.74, p = 0.003), and was reduced (p greater than 0.001) in patients with depressed IgM levels. IgM level in serum may be a useful correlate of splenic phagocytic function in SLE patients.
对15例系统性红斑狼疮（SLE）患者进行了研究，以探讨硫胶体脾脏摄取量与血清免疫球蛋白M水平之间的关系。脾脏功能与IgM水平呈正相关（r = 0.58，p = 0.02），与抗n - DNA抗体滴度呈负相关（r = - 0.74，p = 0.003），且在IgM水平降低的患者中脾脏功能降低（p>0.001）。血清IgM水平可能是SLE患者脾脏吞噬功能的一个有用的相关指标。
