Cumberledge Jeremy D, Anaka Ikenna, Kupec Justin T
Department of Medicine, Section of Digestive Diseases, West Virginia University Hospitals, Morgantown, West Virginia, USA.
BMJ Case Rep. 2019 Jan 29;12(1):e227184. doi: 10.1136/bcr-2018-227184.
We present a case of a healthy 59-year-old woman who presented for a capsule endoscopy to evaluate melaena and iron deficiency anaemia. She had previously underwent an oesophagogastroduodenoscopy and colonoscopy at an outside institution which were unremarkable. Capsule endoscopy showed an ulcerated, bleeding lesion likely in the duodenum. Differential diagnosis included adenocarcinoma, carcinoid tumour, lymphoma, gastrointestinal stromal tumour and metastatic disease. A push enteroscopy was performed after which showed an ulcerated mass in the third portion of the duodenum. Biopsies confirmed adenocarcinoma. Computed tomography of the abdomen showed no signs of distant metastasis and the patient was referred to surgery for evaluation. The patient underwent a pancreaticoduodenectomy, with resection of the mass and negative lymph nodes in all nine that were removed (T3N0). The patient was classified as stage II duodenal adenocarcinoma. Duodenal adenocarcinoma is a rare but clinically significant cause of small bowel bleeding.
我们报告一例59岁健康女性,因进行胶囊内镜检查以评估黑便和缺铁性贫血就诊。她之前在其他机构接受过食管胃十二指肠镜检查和结肠镜检查,结果均无异常。胶囊内镜显示十二指肠可能有一个溃疡出血性病变。鉴别诊断包括腺癌、类癌肿瘤、淋巴瘤、胃肠道间质瘤和转移性疾病。随后进行了推进式小肠镜检查,结果显示十二指肠第三部分有一个溃疡肿块。活检确诊为腺癌。腹部计算机断层扫描未显示远处转移迹象,该患者被转诊至外科进行评估。患者接受了胰十二指肠切除术,切除了肿块,所有切除的9个淋巴结均为阴性(T3N0)。该患者被归类为II期十二指肠腺癌。十二指肠腺癌是小肠出血的一种罕见但具有临床意义的病因。