2008 - 2012年中国肺癌的发病率和死亡率
Incidence and mortality of lung cancer in China, 20082012.
作者信息
Liu Shuzheng, Chen Qiong, Guo Lanwei, Cao Xiaoqin, Sun Xibin, Chen Wanqing, He Jie
机构信息
Henan Cancer Prevention and Control Office, Affiliated Tumor Hospital of Zhengzhou University/Henan Cancer Hospital, Zhengzhou 450008, China.
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100021, China.
出版信息
Chin J Cancer Res. 2018 Dec;30(6):580-587. doi: 10.21147/j.issn.1000-9604.2018.06.02.
OBJECTIVE
To analyze the incidence and mortality rates of lung cancer in China from 2008 to 2012.
METHODS
Incident and death cases of lung cancer were retrieved from the National Central Cancer Registry (NCCR) database collecting from 135 cancer registries in China during 2008-2012. The crude incidence and mortality rates of lung cancer were calculated by area (urban/rural), region (eastern, middle, western), gender and age group (0, 1-4, 5-9, …, 85+). China census in 2000 and Segi's world population were applied for age-standardized rates. JoinPoint (Version 4.5.0.1) model was used for time trend analysis.
RESULTS
The crude incidence rate of lung cancer was 54.66/100,000 which ranked the first in overall cancers. The age-standardized incidence rates by China population (ASIRC) and by World population (ASIRW) were 35.13/100,000 and 34.86/100,000, respectively. The crude mortality of lung cancer in China was 45.60/100,000 and it was the first cause of cancer-related death in overall cancers. The age-standardized mortality rates by Chinese standard population (ASMRC) and by world standard population (ASMRW) were 28.57/100,000 and 28.22/100,000, respectively. Incidence and mortality rates of lung cancer were higher in males than in females and higher in urban areas than in rural areas. Eastern areas had the highest incidence and mortality rates followed by middle and western areas. Incidence and mortality rates of lung cancer retained low level in age groups before 40 years old but increased greatly after and peaked in age group of 80-84. During 2003-2012, the temporal trend of the incidence rate of lung cancer in both sexes in China was general stable (P<0.05). The lung cancer incidence rate increased by 0.71% per year in females (P<0.05) and 2.26% per year in rural areas (P<0.05). The mortality rate of lung cancer decreased slightly annually during 2003-2012 in China (P>0.05). In urban areas, it declined by 0.76% per year (P<0.05), but rose by 2.09% per year (P<0.05) in rural areas.
CONCLUSIONS
Appropriate targeted prevention, early detection and treatment programs should be carried out to control the local burden of lung cancer.
目的
分析2008年至2012年中国肺癌的发病率和死亡率。
方法
从国家中央癌症登记处（NCCR）数据库中检索2008 - 2012年期间中国135个癌症登记处收集的肺癌发病和死亡病例。按地区（城市/农村）、区域（东部、中部、西部）、性别和年龄组（0、1 - 4、5 - 9、…、85岁及以上）计算肺癌的粗发病率和死亡率。采用2000年中国人口普查数据和Segi世界人口数据计算年龄标准化率。使用JoinPoint（版本4.5.0.1）模型进行时间趋势分析。
结果
肺癌的粗发病率为54.66/10万，在所有癌症中排名第一。按中国人口计算的年龄标准化发病率（ASIRC）和按世界人口计算的年龄标准化发病率（ASIRW）分别为35.13/10万和34.86/10万。中国肺癌的粗死亡率为45.60/10万，是所有癌症相关死亡的首要原因。按中国标准人口计算的年龄标准化死亡率（ASMRC）和按世界标准人口计算的年龄标准化死亡率（ASMRW）分别为28.57/10万和28.22/10万。肺癌的发病率和死亡率男性高于女性，城市地区高于农村地区。东部地区的发病率和死亡率最高，其次是中部和西部地区。肺癌的发病率和死亡率在40岁以前的年龄组中保持在较低水平，但40岁以后大幅上升，并在80 - 84岁年龄组达到峰值。2003 - 2012年期间，中国男女肺癌发病率的时间趋势总体稳定（P<0.05）。女性肺癌发病率每年上升0.71%（P<0.05），农村地区每年上升2.26%（P<0.05）。中国2003 - 2012年期间肺癌死亡率每年略有下降（P>0.05）。在城市地区，每年下降0.76%（P<0.05），但在农村地区每年上升2.09%（P<0.05）。
结论
应开展适当的针对性预防、早期检测和治疗项目，以控制当地的肺癌负担。
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