Bulğurcu Suphi, Çukurova İbrahim
Department of Otorhinolaryngology, Sultan Abdülhamid Han Training and Research Hospital, İstanbul, Turkey.
Department of Otorhinolaryngology, Tepecik Training and Research Hospital, İzmir, Turkey.
Turk Arch Otorhinolaryngol. 2018 Dec;56(4):217-220. doi: 10.5152/tao.2018.3605. Epub 2018 Dec 25.
There is still no consensus on the effect of early oral feeding and nasogastric tube feeding on the development of pharyngocutaneous fistula (PCF) after total laryngectomy. The aim of the present study was to compare the effects of early oral feeding and nasogastric tube (NGT) feeding after total laryngectomy on the incidence of PCF.
A total of 59 male and three female patients with a mean age of 61.65 (range 44-77) years who underwent total laryngectomy and bilateral neck dissection between May 2010 and June 2016 were evaluated retrospectively. Thirty-two patients started oral feeding on postoperative day three, and 30 patients started NGT feeding on postoperative day one following oral feeding on 7th day. Besides the investigation of the factors which can affect PCF formation, the incidence of PCF was also determined between the two groups of patients.
Only preoperative albumin value was different between the groups in the determination of factors which can affect development of PCF. No statistical difference was found between the two groups in terms of the development of PCF and the length of hospital stay (p>0.05).
To start oral feeding on postoperative day three or with a NGT feeding on postoperative day one following oral feeding on day seven did not affect the development of PCF and the length of hospital stay in patients who underwent total laryngectomy.
对于全喉切除术后早期经口喂养和鼻胃管喂养对咽皮瘘（PCF）发生发展的影响，目前仍未达成共识。本研究的目的是比较全喉切除术后早期经口喂养和鼻胃管（NGT）喂养对PCF发生率的影响。
回顾性评估2010年5月至2016年6月期间接受全喉切除术和双侧颈清扫术的59例男性和3例女性患者，平均年龄61.65岁（范围44 - 77岁）。32例患者术后第3天开始经口喂养，30例患者术后第1天开始鼻胃管喂养，第7天改为经口喂养。除了调查可能影响PCF形成的因素外，还确定了两组患者中PCF的发生率。
在确定可能影响PCF发生发展的因素时，两组之间仅术前白蛋白值存在差异。两组在PCF的发生发展和住院时间方面未发现统计学差异（p>0.05）。
全喉切除术后患者在术后第3天开始经口喂养或在第7天经口喂养后第1天开始鼻胃管喂养，均不影响PCF的发生发展和住院时间。
