Arias Mauricio A, Clark John
Epsom and St Helier University Hospitals NHS Trust, Wrythe Lane, Sutton, SM5 1AA, UK.
IDCases. 2019 Jan 9;15:e00486. doi: 10.1016/j.idcr.2019.e00486. eCollection 2019.
is a Gram-negative coccobacilli which is often an environmental organism. However, infection of patients usually with underlying immunosuppression has been described in the last decades, mainly due to the emergence of diagnostic molecular methods.
We describe here a case of peritonitis in a patient undergoing peritoneal dialysis. Turbidity of the peritoneal dialysate was the sole clinical manifestation. Inflammatory markers were not raised. A peritoneal fluid specimen showed increased white-cell count, but no organisms were seen on Gram stain. identified as the infectious agent. Patient was successfully treated with gentamicin. Minimum inhibitory concentration analysis suggested to be sensitive to aminoglycosides and specific betalactams but not to ciprofloxacin and ceftazidime, in line with previous literature.
This case of peritoneal-dialysis peritonitis contributes to accumulating evidence on the emergent role of this organism as a relevant human pathogen. It also provides information about antibiotic resistance patterns that helps to guide therapy more specifically and effectively.
是一种革兰氏阴性球杆菌，通常为环境微生物。然而，在过去几十年中，已报道了通常伴有潜在免疫抑制的患者感染情况，这主要归因于诊断性分子方法的出现。
我们在此描述一例接受腹膜透析患者的腹膜炎病例。腹膜透析液浑浊是唯一的临床表现。炎症标志物未升高。一份腹膜液标本显示白细胞计数增加，但革兰氏染色未发现微生物。被鉴定为感染病原体。患者接受庆大霉素治疗成功。最低抑菌浓度分析表明对氨基糖苷类和特定β-内酰胺类敏感，但对环丙沙星和头孢他啶不敏感，这与先前文献一致。
该例腹膜透析相关性腹膜炎病例为这种微生物作为重要人类病原体的新出现作用积累了证据。它还提供了有关抗生素耐药模式的信息，有助于更具体有效地指导治疗。
