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附件口息肉:单机构 691 例病变研究。

Appendix orifice polyps: a study of 691 lesions at a single institution.

机构信息

Medical Research Institute, University Of Alexandria, Alexandria, Egypt.

Department of Colorectal Surgery, Digestive Diseases and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.

出版信息

Int J Colorectal Dis. 2019 Apr;34(4):711-718. doi: 10.1007/s00384-019-03251-z. Epub 2019 Jan 30.

DOI:10.1007/s00384-019-03251-z
PMID:30701384
Abstract

PURPOSE

Data on the management of appendix orifice lesions are limited. We present our experience on the management of appendix orifice lesions focusing on the range of size, histology, treatment, and outcomes for polyps at the appendix orifice.

METHODS

Retrospective descriptive study at a tertiary referral center.

PATIENTS

Those having appendix orifice lesion removed and sent for histology between 2000 and 2017.

INTERVENTIONS(S): Polypectomy, surgery.

MAIN OUTCOME MEASURES

Polyp size, shape, histology, treatment.

RESULTS

In total, 691 patients matched our inclusion criteria. Screening was the most common indication for colonoscopy (49.1%). Mean size was 10.1 mm. The most common excision method was cold biopsy forceps (36.3%), followed by hot snare (9.3%), cold snare (8.5%), jumbo cold forceps (6.7%), hot biopsy (6.8%), and endoscopic mucosal resection (EMR)/endoscopic submucosal dissection (ESD) (4%). Recurrence was seen in 19/184 (10.3%) patients. Index polyps ≥ 10 mm had a significantly higher risk of recurrence compared to those ≤ 5 mm (odds ratio 3.2 95% CI 1.1-9.2, p = 0.027). None of the patients had complications. Surgery was performed in 45/691 (6.5%). Polyps > 5 mm (41/45) were more likely to require surgery than polyps ≤ 5 mm (4/45 6.67%), p < 0.001.

LIMITATIONS

Retrospective study.

CONCLUSION

Appendix orifice polyps can usually be managed by conventional endoscopic polypectomy methods without the need for ESD.

摘要

目的

关于阑尾口病变处理的数据有限。我们介绍了我们在阑尾口病变处理方面的经验,重点介绍了阑尾口息肉的大小、组织学、治疗和结果范围。

方法

在一家三级转诊中心进行回顾性描述性研究。

患者

在 2000 年至 2017 年间,有阑尾口病变切除并进行组织学检查的患者。

干预措施

息肉切除术,手术。

主要观察指标

息肉大小、形状、组织学、治疗。

结果

共有 691 名患者符合我们的纳入标准。筛查是结肠镜检查最常见的适应证(49.1%)。平均大小为 10.1mm。最常见的切除方法是冷活检钳(36.3%),其次是热圈套器(9.3%)、冷圈套器(8.5%)、巨冷钳(6.7%)、热活检(6.8%)和内镜黏膜切除术(EMR)/内镜黏膜下剥离术(ESD)(4%)。184 名患者中有 19 名(10.3%)复发。指数息肉≥10mm 与≤5mm 的患者相比,复发风险显著更高(比值比 3.2,95%可信区间 1.1-9.2,p=0.027)。无并发症发生。691 名患者中有 45 名(6.5%)接受了手术。>5mm 的息肉(41/45)比≤5mm 的息肉(4/45,6.67%)更有可能需要手术(p<0.001)。

局限性

回顾性研究。

结论

阑尾口息肉通常可以通过传统的内镜息肉切除术方法进行治疗,而无需 ESD。

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本文引用的文献

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Dig Dis Sci. 2017 Nov;62(11):3138-3148. doi: 10.1007/s10620-017-4760-2. Epub 2017 Sep 21.
2
Endoscopic submucosal dissection of cecal lesions in proximity to the appendiceal orifice.经肛门内镜微创手术治疗阑尾开口附近盲肠病变。
Endoscopy. 2016 Sep;48(9):829-36. doi: 10.1055/s-0042-110396. Epub 2016 Jul 28.
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Value of screening endoscopy in evaluation of esophageal, gastric and colon cancers.
回盲瓣保留的回肠-盲肠切除术治疗不适合息肉切除术的良性盲肠息肉。
JSLS. 2021 Apr-Jun;25(2). doi: 10.4293/JSLS.2021.00023.
4
"Obscure" Appendiceal Orifice Polyps Can Be Challenging to Identify by Colonoscopy.“隐匿性”阑尾开口息肉通过结肠镜检查可能难以识别。
Case Rep Gastroenterol. 2020 Jan 20;14(1):15-26. doi: 10.1159/000505482. eCollection 2020 Jan-Apr.
筛查性内镜检查在食管癌、胃癌和结肠癌评估中的价值。
World J Gastroenterol. 2015 Sep 7;21(33):9693-706. doi: 10.3748/wjg.v21.i33.9693.
4
Predictive factors for technically difficult endoscopic submucosal dissection in the colorectum.结直肠内镜黏膜下剥离术技术难度的预测因素
Endoscopy. 2014 Oct;46(10):862-70. doi: 10.1055/s-0034-1377205. Epub 2014 Sep 10.
5
Techniques of endoscopic submucosal dissection: application for the Western endoscopist?内镜黏膜下剥离术技术:适用于西方内镜医师吗?
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Colonoscopic polypectomy and associated techniques.结肠镜息肉切除术及相关技术。
World J Gastroenterol. 2010 Aug 7;16(29):3630-7. doi: 10.3748/wjg.v16.i29.3630.
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Laparoscopic vs. colonoscopic removal of a large polyp.
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