Department of Radiology, Stony Brook University, Stony Brook, New York, USA.
Department of Biomedical Engineering, Stony Brook University, Stony Brook, New York, USA.
J Magn Reson Imaging. 2019 Sep;50(3):702-718. doi: 10.1002/jmri.26672. Epub 2019 Jan 30.
Although radiography continues to play a critical role in osseous tumor assessment, there have been remarkable advances in cross-sectional imaging. MRI has taken a lead in this assessment due to high tissue contrast and spatial resolution, which are well suited for bone lesion assessment. More recently, although somewhat lagging other organ systems, quantitative parameters have shown promising potential as biomarkers for osseous tumors. Among these sequences are chemical shift imaging (CSI), apparent diffusion coefficient (ADC), and intravoxel incoherent motion (IVIM) from diffusion-weighted imaging (DWI), quantitative dynamic contrast enhanced (DCE)-MRI, and magnetic resonance spectroscopy (MRS). In this article, we review the background and recent roles of these quantitative MRI biomarkers for osseous tumors. Level of Evidence: 3 Technical Efficacy Stage: 3 J. MAGN. RESON. IMAGING 2019. J. Magn. Reson. Imaging 2019;50:702-718.
尽管放射学在骨肿瘤评估中继续发挥着关键作用，但在横断面成像方面已经取得了显著的进展。由于具有较高的组织对比度和空间分辨率，MRI 在这种评估中处于领先地位，非常适合骨病变评估。最近，尽管在其他器官系统方面有些滞后，但定量参数已显示出作为骨肿瘤生物标志物的有前途的潜力。这些序列包括化学位移成像（CSI）、表观扩散系数（ADC）和来自扩散加权成像（DWI）的体素内不相干运动（IVIM）、定量动态对比增强（DCE）-MRI 和磁共振波谱（MRS）。在本文中，我们回顾了这些定量 MRI 骨肿瘤生物标志物的背景和最新作用。证据水平：3 技术功效阶段：3 J. MAGN. RESON. IMAGING 2019. J. 磁共振成像 2019;50:702-718.
